Product Information
DIPHENHYDRAMINE 12.5 MG/5 ML is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0175 per ML under NDC 57237030516. Its NADAC has been published 174 times since Apr 26, 2023.
Strength
12.5 mg/5mL
Manufacturer
Rising Pharma Holdings Inc.NDC
57237030516
Classification
Generic
Dosage Form
LIQUID
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M009.50On Market Since
12/19/2022
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has been published 174 times since Apr 26, 2023, and over the history we have for it it has declined 14.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0175 per ML |
|---|---|
| All-time high | $0.0204 (May 10, 2023) |
| All-time low | $0.0118 (Nov 20, 2024) |
| 52-week high | $0.0178 |
| 52-week low | $0.0122 |
| Median price | $0.0131 |
| Average price | $0.0141 |
| Largest weekly change | -27.1% (Mar 20, 2024) |
| Weeks tracked | 174 |
| Tracking since | Apr 26, 2023 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 11% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 12.5 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 12.5 MG/5 ML, manufactured by Rising Pharma Holdings Inc., is $0.0175 per ML (NDC 57237030516), effective Aug 19, 2026.
How has the price of DIPHENHYDRAMINE 12.5 MG/5 ML changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has declined 14.2%. It has been tracked across 174 weekly CMS publications since Apr 26, 2023.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 12.5 MG/5 ML?
Since Apr 26, 2023, the NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has ranged from a low of $0.0118 (Nov 20, 2024) to a high of $0.0204 (May 10, 2023), with a median of $0.0131 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 12.5 MG/5 ML?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, QC CHILD ALLERGY 12.5 MG/5 ML, is $0.0155 per ML — about 11% below DIPHENHYDRAMINE 12.5 MG/5 ML.
Who manufactures DIPHENHYDRAMINE 12.5 MG/5 ML?
DIPHENHYDRAMINE 12.5 MG/5 ML (NDC 57237030516) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.