Product Information
DIPHENHYDRAMINE 12.5 MG/5 ML is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0170 per ML under NDC 57237030516. Its NADAC has been published 166 times since Apr 26, 2023.
Strength
12.5 mg/5mL
Manufacturer
Rising Pharma Holdings Inc.NDC
57237030516
Classification
Generic
Dosage Form
LIQUID
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M009.50On Market Since
12/19/2022
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has been published 166 times since Apr 26, 2023, and over the history we have for it it has declined 16.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0170 per ML |
|---|---|
| All-time high | $0.0204 (May 10, 2023) |
| All-time low | $0.0118 (Nov 20, 2024) |
| 52-week high | $0.0178 |
| 52-week low | $0.0121 |
| Median price | $0.0129 |
| Average price | $0.0140 |
| Largest weekly change | -27.1% (Mar 20, 2024) |
| Weeks tracked | 166 |
| Tracking since | Apr 26, 2023 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 12.5 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 12.5 MG/5 ML, manufactured by Rising Pharma Holdings Inc., is $0.0170 per ML (NDC 57237030516), effective Jun 24, 2026.
How has the price of DIPHENHYDRAMINE 12.5 MG/5 ML changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has declined 16.6%. It has been tracked across 166 weekly CMS publications since Apr 26, 2023.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 12.5 MG/5 ML?
Since Apr 26, 2023, the NADAC for DIPHENHYDRAMINE 12.5 MG/5 ML has ranged from a low of $0.0118 (Nov 20, 2024) to a high of $0.0204 (May 10, 2023), with a median of $0.0129 per ML.
Are there cheaper alternatives to DIPHENHYDRAMINE 12.5 MG/5 ML?
Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, CHILD'S ALLERGY 12.5 MG/5 ML, is $0.0143 per ML — about 16% below DIPHENHYDRAMINE 12.5 MG/5 ML.
Who manufactures DIPHENHYDRAMINE 12.5 MG/5 ML?
DIPHENHYDRAMINE 12.5 MG/5 ML (NDC 57237030516) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.
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