Clozapine
44 NDCs across 8 manufacturers|42 Generic,2 Brand
Clozapine is used to treat bipolar disorder, psychotic disorders and schizophrenia, per the National Library of Medicine's MED-RT classification.
▸ More about this market▾ Less
The brand product was first FDA-approved on Sep 26, 1989, and the first generic was approved Aug 30, 1996. FDA's Orange Book lists 32 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $108 million on Clozapine across 1.2 million claims for 69,000 beneficiaries.
Clozapine is available as 44 NDCs from 8 manufacturers (42 generic, 2 brand), with NADAC prices from $0.24 to $21.20 per EA — the most expensive product costs about 87× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
44
42G / 2B
Manufacturers
8
competing in market
Price Spread
$0.24 – $21.20
per EA
7d Activity
avg -0.0% WoW · of 44 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Explore this market from other angles
Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.
Top supplier
Aurobindo Pharma Limited manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Atypical Antipsychotic class view
See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.
Trend hub
Latest market trends
Move from this single molecule into the current cross-market mover and volatility view.
Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
8 manufacturers producing CLOZAPINE
Frequently Asked Questions
What is Clozapine used to treat?
Clozapine is used to treat bipolar disorder, psychotic disorders and schizophrenia, per the National Library of Medicine's MED-RT classification.
When did Clozapine become available as a generic?
FDA approved the first generic Clozapine (ANDA) on Aug 30, 1996. The Orange Book currently lists 32 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Clozapine?
In 2024, Medicare Part D spent $108 million on Clozapine across 1.2 million claims for 69,000 beneficiaries.
How many Clozapine products are on the market?
The Clozapine drug market contains 44 NDCs from 8 manufacturers — 42 generic and 2 brand products.
What is the price range for Clozapine?
NADAC reference prices for Clozapine range from $0.2424 to $21.2033 per EA — the most expensive product costs about 87× the cheapest.
Is generic Clozapine cheaper than brand?
The average generic NADAC for Clozapine is $4.4506 per EA, versus $11.6889 for brand-labeled products — brand versions average about 2.6× the generic price.
Which manufacturers make Clozapine?
8 manufacturers list Clozapine in NADAC. Ranked by number of NDCs, the largest are Aurobindo Pharma Limited (9), Mylan Pharmaceuticals Inc. (9), Teva Pharmaceuticals USA Inc. (8), Mylan Institutional LLC (4), American Health Packaging (4).
How has the price of Clozapine changed recently?
Over the past 7 days, 17 Clozapine NDCs rose and 17 fell, with a market-wide average change of -0.0%.