Lorazepam
70 NDCs across 17 manufacturers|63 Generic,7 Brand
Lorazepam is used to treat anxiety disorders, catatonia, depressive disorder, partial epilepsies, psychotic disorders and sleep initiation and maintenance disorders, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Aug 9, 1985. FDA's Orange Book lists 27 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $78 million on Lorazepam across 8.1 million claims for 1.9 million beneficiaries.
Lorazepam is available as 70 NDCs from 17 manufacturers (63 generic, 7 brand), with NADAC prices from $0.02 to $75.96 per EA — the most expensive product costs about 3,735× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Active FDA drug shortage
11 Lorazepam presentations are currently listed in FDA's drug shortage database (first posted May 3, 2018). Shortages can move NADAC prices in the following weeks.
Total NDCs
70
63G / 7B
Manufacturers
17
competing in market
Price Spread
$0.02 – $75.96
per EA, 58 of 70 NDCs
7d Activity
avg +2.7% WoW · of 70 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Sun Pharmaceutical Industries Inc. manufacturer profile
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Lead class
Benzodiazepine class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
17 manufacturers producing LORAZEPAM(2 pricing outliers)
Frequently Asked Questions
What is Lorazepam used to treat?
Lorazepam is used to treat anxiety disorders, catatonia, depressive disorder, partial epilepsies, psychotic disorders and sleep initiation and maintenance disorders, per the National Library of Medicine's MED-RT classification.
When did Lorazepam become available as a generic?
FDA approved the first generic Lorazepam (ANDA) on Aug 9, 1985. The Orange Book currently lists 27 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Lorazepam?
In 2024, Medicare Part D spent $78 million on Lorazepam across 8.1 million claims for 1.9 million beneficiaries.
Is Lorazepam in shortage?
Yes — FDA's drug shortage database currently lists 11 Lorazepam presentations with status "Current", first posted May 3, 2018.
How many Lorazepam products are on the market?
The Lorazepam drug market contains 70 NDCs from 17 manufacturers — 63 generic and 7 brand products.
What is the price range for Lorazepam?
NADAC reference prices for Lorazepam range from $0.0203 to $75.9602 per EA — the most expensive product costs about 3,735× the cheapest. 12 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Is generic Lorazepam cheaper than brand?
The average generic NADAC for Lorazepam is $0.0476 per EA, versus $30.7626 for brand-labeled products — brand versions average about 646× the generic price.
Which manufacturers make Lorazepam?
17 manufacturers list Lorazepam in NADAC. Ranked by number of NDCs, the largest are Sun Pharmaceutical Industries Inc. (12), Leading Pharma, LLC (9), Teva Pharmaceuticals USA Inc. (9), Aurolife Pharma LLC (7), Hikma Pharmaceuticals USA Inc. (6).
How has the price of Lorazepam changed recently?
Over the past 7 days, 48 Lorazepam NDCs rose and 8 fell, with a market-wide average change of +2.7%.