Ramelteon
25 NDCs across 14 manufacturers|23 Generic,2 Brand
Ramelteon is used to treat sleep initiation and maintenance disorders, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Jul 22, 2005, and the first generic was approved Jul 26, 2013. FDA's Orange Book lists 11 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $25 million on Ramelteon across 224,000 claims for 66,000 beneficiaries.
Ramelteon is available as 25 NDCs from 14 manufacturers (23 generic, 2 brand), with NADAC prices from $0.66 to $12.42 per EA — the most expensive product costs about 19× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
25
23G / 2B
Manufacturers
14
competing in market
Price Spread
$0.66 – $12.42
per EA
7d Activity
avg +0.3% WoW · of 25 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Xiromed LLC manufacturer profile
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Lead class
Melatonin Receptor Agonist class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
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Manufacturer Breakdown
14 manufacturers producing RAMELTEON(4 pricing outliers)
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
ROZEREM 8 MG TABLET | $12.4169 per EA | -0.12% |
ROZEREM 8 MG TABLET | $12.4169 per EA | -0.12% |
RAMELTEON 8 MG TABLET | $0.6898 per EA | — |
RAMELTEON 8 MG TABLET | $0.6671 per EA | — |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6598 per EA | +0.36% |
RAMELTEON 8 MG TABLET | $0.6575 per EA | — |
RAMELTEON 8 MG TABLET | $0.6575 per EA | — |
RAMELTEON 8 MG TABLET | $0.6575 per EA | — |
Frequently Asked Questions
What is Ramelteon used to treat?
Ramelteon is used to treat sleep initiation and maintenance disorders, per the National Library of Medicine's MED-RT classification.
When did Ramelteon become available as a generic?
FDA approved the first generic Ramelteon (ANDA) on Jul 26, 2013. The Orange Book currently lists 11 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Ramelteon?
In 2024, Medicare Part D spent $25 million on Ramelteon across 224,000 claims for 66,000 beneficiaries.
How many Ramelteon products are on the market?
The Ramelteon drug market contains 25 NDCs from 14 manufacturers — 23 generic and 2 brand products.
What is the price range for Ramelteon?
NADAC reference prices for Ramelteon range from $0.6575 to $12.4169 per EA — the most expensive product costs about 19× the cheapest.
Is generic Ramelteon cheaper than brand?
The average generic NADAC for Ramelteon is $0.6611 per EA, versus $12.4169 for brand-labeled products — brand versions average about 19× the generic price.
Which manufacturers make Ramelteon?
14 manufacturers list Ramelteon in NADAC. Ranked by number of NDCs, the largest are Xiromed LLC (3), Takeda Pharmaceuticals America, Inc. (2), Dr. Reddy's Laboratories Inc. (2), Micro Labs Limited (2), TruPharma LLC (2).
How has the price of Ramelteon changed recently?
Over the past 7 days, 18 Ramelteon NDCs rose and 2 fell, with a market-wide average change of +0.3%.