Product Information
BUTORPHANOL 10 MG/ML SPRAY is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $14.8006 per ML under NDC 00054309036. Its NADAC has been published 658 times since Nov 28, 2013.
Strength
10 mg/mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00054309036
Classification
Generic
Dosage Form
SPRAY, METERED
Route
NASAL
Last Updated
6/17/2026
Active Ingredients
BUTORPHANOL TARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA075824On Market Since
3/12/2002
Pharmacological Classes
Price Statistics
The NADAC for BUTORPHANOL 10 MG/ML SPRAY has been published 658 times since Nov 28, 2013, and over the history we have for it it has risen 190.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $14.8006 per ML |
|---|---|
| All-time high | $16.0178 (Nov 12, 2025) |
| All-time low | $5.0940 (Nov 28, 2013) |
| 52-week high | $16.0178 |
| 52-week low | $13.2510 |
| Median price | $13.6480 |
| Average price | $13.3131 |
| Largest weekly change | +67.0% (Mar 19, 2014) |
| Weeks tracked | 658 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BUTORPHANOL 10 MG/ML SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for BUTORPHANOL 10 MG/ML SPRAY, manufactured by Hikma Pharmaceuticals USA Inc., is $14.8006 per ML (NDC 00054309036), effective Jul 1, 2026.
How has the price of BUTORPHANOL 10 MG/ML SPRAY changed over time?
Over the history we have for it, the NADAC for BUTORPHANOL 10 MG/ML SPRAY has risen 190.5%. It has been tracked across 658 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for BUTORPHANOL 10 MG/ML SPRAY?
Since Nov 28, 2013, the NADAC for BUTORPHANOL 10 MG/ML SPRAY has ranged from a low of $5.0940 (Nov 28, 2013) to a high of $16.0178 (Nov 12, 2025), with a median of $13.6480 per ML.
Are there cheaper alternatives to BUTORPHANOL 10 MG/ML SPRAY?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as BUTORPHANOL 10 MG/ML SPRAY, but none are currently priced below it.
Who manufactures BUTORPHANOL 10 MG/ML SPRAY?
BUTORPHANOL 10 MG/ML SPRAY (NDC 00054309036) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.
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