Product Information
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET is a generic product labeled by PAI Holdings LLC, priced at $0.6379 per EA under NDC 00121203630. Its NADAC has been published 129 times since Mar 6, 2024.
FDA first approved this application on Oct 16, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET
buprenorphine hydrochloride and naloxone hydrochlorideStrength
8; 2 mg/1; mg/1
Manufacturer
PAI Holdings LLCNDC
00121203630
Classification
Generic
Dosage Form
TABLET
Route
SUBLINGUAL
Effective Date
8/19/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDE; NALOXONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA204431FDA Approved
10/16/2015
TE Code
AB
On Market Since
9/5/2023
Pharmacological Classes
Price Statistics
The NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has been published 129 times since Mar 6, 2024, and over the history we have for it it has declined 36.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6379 per EA |
|---|---|
| All-time high | $1.0433 (Apr 10, 2024) |
| All-time low | $0.6322 (Jul 22, 2026) |
| 52-week high | $0.7333 |
| 52-week low | $0.6322 |
| Median price | $0.7254 |
| Average price | $0.7497 |
| Largest weekly change | +29.6% (Aug 21, 2024) |
| Weeks tracked | 129 |
| Tracking since | Mar 6, 2024 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the buprenorphine hydrochloride and naloxone hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET, manufactured by PAI Holdings LLC, is $0.6379 per EA (NDC 00121203630), effective Aug 19, 2026.
How has the price of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET changed over time?
Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has declined 36.5%. It has been tracked across 129 weekly CMS publications since Mar 6, 2024.
What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
Since Mar 6, 2024, the NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has ranged from a low of $0.6322 (Jul 22, 2026) to a high of $1.0433 (Apr 10, 2024), with a median of $0.7254 per EA.
Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
No other NADAC-published product currently shares the active ingredient and strength of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET (NDC 00121203630) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.