Product Information

ESTRADIOL VALERATE 200 MG/5 ML is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $35.0598 per ML under NDC 00143929101. Its NADAC has been published 268 times since Jul 7, 2021.

FDA first approved this application on Apr 21, 2020. Its Orange Book therapeutic-equivalence code is AO.

ESTRADIOL VALERATE 200 MG/5 ML

Estradiol Valerate
$35.0598per ML

Strength

40 mg/mL

NDC

00143929101

Classification

Generic

Dosage Form

INJECTION

Route

INTRAMUSCULAR

Effective Date

8/19/2026

Active Ingredients

ESTRADIOL VALERATE

Approval Type

Generic (ANDA)

FDA Application

ANDA203723

FDA Approved

4/21/2020

TE Code

AO

On Market Since

4/21/2020

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for ESTRADIOL VALERATE 200 MG/5 ML has been published 268 times since Jul 7, 2021, and over the history we have for it it has risen 8.8%. The table below summarizes its recorded NADAC range and movement.

Current price$35.0598 per ML
All-time high$38.6398 (Nov 12, 2025)
All-time low$24.9823 (Nov 20, 2024)
52-week high$38.6398
52-week low$33.6338
Median price$33.7100
Average price$33.5191
Largest weekly change+33.8% (Oct 18, 2023)
Weeks tracked268
Tracking sinceJul 7, 2021

Price History

1W

+0.6%

1M

+0.6%

3M

+4.2%

6M

-1.5%

1Y

-0.5%

3Y

+4.0%

5Y

+8.8%

All

+8.8%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol Valerate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of ESTRADIOL VALERATE 200 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL VALERATE 200 MG/5 ML, manufactured by Hikma Pharmaceuticals USA Inc., is $35.0598 per ML (NDC 00143929101), effective Aug 19, 2026.

How has the price of ESTRADIOL VALERATE 200 MG/5 ML changed over time?

Over the history we have for it, the NADAC for ESTRADIOL VALERATE 200 MG/5 ML has risen 8.8%. It has been tracked across 268 weekly CMS publications since Jul 7, 2021.

What are the highest and lowest recorded NADAC prices for ESTRADIOL VALERATE 200 MG/5 ML?

Since Jul 7, 2021, the NADAC for ESTRADIOL VALERATE 200 MG/5 ML has ranged from a low of $24.9823 (Nov 20, 2024) to a high of $38.6398 (Nov 12, 2025), with a median of $33.7100 per ML.

Are there cheaper alternatives to ESTRADIOL VALERATE 200 MG/5 ML?

No other NADAC-published product currently shares the active ingredient and strength of ESTRADIOL VALERATE 200 MG/5 ML in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ESTRADIOL VALERATE 200 MG/5 ML?

ESTRADIOL VALERATE 200 MG/5 ML (NDC 00143929101) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.