Product Information

DAPTOMYCIN 500 MG VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $22.6865 per EA under NDC 00143944401. Its NADAC has been published 38 times since Dec 3, 2025.

FDA first approved this application on Jun 15, 2016. Its Orange Book therapeutic-equivalence code is AP.

DAPTOMYCIN 500 MG VIAL

Daptomycin
$22.6865per EA

Strength

500 mg/10mL

NDC

00143944401

Classification

Generic

Dosage Form

INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION

Route

INTRAVENOUS

Effective Date

8/19/2026

Active Ingredients

DAPTOMYCIN

Approval Type

Generic (ANDA)

FDA Application

ANDA206005

FDA Approved

6/15/2016

TE Code

AP

On Market Since

9/30/2025

Pharmacological Classes

Price Statistics

The NADAC for DAPTOMYCIN 500 MG VIAL has been published 38 times since Dec 3, 2025, and over the history we have for it it has risen 12.9%. The table below summarizes its recorded NADAC range and movement.

Current price$22.6865 per EA
All-time high$22.6865 (Aug 19, 2026)
All-time low$20.1020 (Dec 3, 2025)
52-week high$22.6865
52-week low$20.1020
Median price$20.7686
Average price$21.0524
Largest weekly change+8.9% (Aug 19, 2026)
Weeks tracked38
Tracking sinceDec 3, 2025

Price History

1W

+8.9%

1M

+8.9%

3M

+3.8%

6M

+9.2%

1Y

N/A

3Y

N/A

5Y

N/A

All

+12.9%

Generic Alternatives

The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 8% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DAPTOMYCIN 500 MG VIAL?

The current National Average Drug Acquisition Cost (NADAC) for DAPTOMYCIN 500 MG VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $22.6865 per EA (NDC 00143944401), effective Aug 19, 2026.

How has the price of DAPTOMYCIN 500 MG VIAL changed over time?

Over the history we have for it, the NADAC for DAPTOMYCIN 500 MG VIAL has risen 12.9%. It has been tracked across 38 weekly CMS publications since Dec 3, 2025.

What are the highest and lowest recorded NADAC prices for DAPTOMYCIN 500 MG VIAL?

Since Dec 3, 2025, the NADAC for DAPTOMYCIN 500 MG VIAL has ranged from a low of $20.1020 (Dec 3, 2025) to a high of $22.6865 (Aug 19, 2026), with a median of $20.7686 per EA.

Are there cheaper alternatives to DAPTOMYCIN 500 MG VIAL?

Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DAPTOMYCIN 500 MG VIAL, is $20.7686 per EA — about 8% below DAPTOMYCIN 500 MG VIAL.

Who manufactures DAPTOMYCIN 500 MG VIAL?

DAPTOMYCIN 500 MG VIAL (NDC 00143944401) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.