Product Information
VAGIFEM 10 MCG VAGINAL TAB is a brand product labeled by Novo Nordisk, priced at $20.3247 per EA under NDC 00169517603. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Mar 26, 1999. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10 ug/1
Manufacturer
Novo NordiskNDC
00169517603
Classification
Brand
Dosage Form
INSERT
Route
VAGINAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA020908FDA Approved
3/26/1999
TE Code
AB
On Market Since
1/11/2010
Pharmacological Classes
Price Statistics
The NADAC for VAGIFEM 10 MCG VAGINAL TAB has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 114.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $20.3247 per EA |
|---|---|
| All-time high | $20.5477 (Apr 10, 2019) |
| All-time low | $9.4714 (Nov 28, 2013) |
| 52-week high | $20.3573 |
| 52-week low | $20.3235 |
| Median price | $20.3934 |
| Average price | $19.2580 |
| Largest weekly change | +19.9% (Apr 8, 2015) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Novo Nordisk manufacturer profile
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Therapeutic class
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Trend hub
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of VAGIFEM 10 MCG VAGINAL TAB?
The current National Average Drug Acquisition Cost (NADAC) for VAGIFEM 10 MCG VAGINAL TAB, manufactured by Novo Nordisk, is $20.3247 per EA (NDC 00169517603), effective Sep 30, 2026.
How has the price of VAGIFEM 10 MCG VAGINAL TAB changed over time?
Over the history we have for it, the NADAC for VAGIFEM 10 MCG VAGINAL TAB has risen 114.6%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for VAGIFEM 10 MCG VAGINAL TAB?
Since Nov 28, 2013, the NADAC for VAGIFEM 10 MCG VAGINAL TAB has ranged from a low of $9.4714 (Nov 28, 2013) to a high of $20.5477 (Apr 10, 2019), with a median of $20.3934 per EA.
Are there cheaper alternatives to VAGIFEM 10 MCG VAGINAL TAB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as VAGIFEM 10 MCG VAGINAL TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures VAGIFEM 10 MCG VAGINAL TAB?
VAGIFEM 10 MCG VAGINAL TAB (NDC 00169517603) is labeled by Novo Nordisk, and CMS classifies it as a brand product.