Product Information
IMVEXXY 10 MCG MAINTENANCE PAK is a brand product labeled by Mayne Pharma, priced at $27.0902 per EA under NDC 68308074808. Its NADAC has been published 72 times since Apr 9, 2025.
FDA first approved this application on May 29, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the estradiol market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
10 ug/1
Manufacturer
Mayne PharmaNDC
68308074808
Classification
Brand
Dosage Form
INSERT
Route
VAGINAL
Effective Date
6/1/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA208564FDA Approved
5/29/2018
TE Code
AB
On Market Since
12/15/2023
Pharmacological Classes
Price Statistics
The NADAC for IMVEXXY 10 MCG MAINTENANCE PAK has been published 72 times since Apr 9, 2025, and over the history we have for it it has risen 4.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $27.0902 per EA |
|---|---|
| All-time high | $27.0902 (Aug 19, 2026) |
| All-time low | $25.7671 (Feb 18, 2026) |
| 52-week high | $27.0902 |
| 52-week low | $25.7671 |
| Median price | $25.8099 |
| Average price | $26.0193 |
| Largest weekly change | +5.0% (Jun 3, 2026) |
| Weeks tracked | 72 |
| Tracking since | Apr 9, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 25% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of IMVEXXY 10 MCG MAINTENANCE PAK?
The current National Average Drug Acquisition Cost (NADAC) for IMVEXXY 10 MCG MAINTENANCE PAK, manufactured by Mayne Pharma, is $27.0902 per EA (NDC 68308074808), effective Aug 19, 2026.
How has the price of IMVEXXY 10 MCG MAINTENANCE PAK changed over time?
Over the history we have for it, the NADAC for IMVEXXY 10 MCG MAINTENANCE PAK has risen 4.7%. It has been tracked across 72 weekly CMS publications since Apr 9, 2025.
What are the highest and lowest recorded NADAC prices for IMVEXXY 10 MCG MAINTENANCE PAK?
Since Apr 9, 2025, the NADAC for IMVEXXY 10 MCG MAINTENANCE PAK has ranged from a low of $25.7671 (Feb 18, 2026) to a high of $27.0902 (Aug 19, 2026), with a median of $25.8099 per EA.
Are there cheaper alternatives to IMVEXXY 10 MCG MAINTENANCE PAK?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, VAGIFEM 10 MCG VAGINAL TAB, is $20.3235 per EA — about 25% below IMVEXXY 10 MCG MAINTENANCE PAK.
Who manufactures IMVEXXY 10 MCG MAINTENANCE PAK?
IMVEXXY 10 MCG MAINTENANCE PAK (NDC 68308074808) is labeled by Mayne Pharma, and CMS classifies it as a brand product.