Product Information
ISOTRETINOIN 30 MG CAPSULE is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $4.1763 per EA under NDC 00245057301. Its NADAC has been published 195 times since Feb 9, 2022.
Strength
30 mg/1
Manufacturer
Upsher-Smith Laboratories LLCNDC
00245057301
Classification
Generic
Dosage Form
CAPSULE, LIQUID FILLED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ISOTRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA212333On Market Since
9/21/2021
Pharmacological Classes
Price Statistics
The NADAC for ISOTRETINOIN 30 MG CAPSULE has been published 195 times since Feb 9, 2022, and over the history we have for it it has declined 84.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $4.1763 per EA |
|---|---|
| All-time high | $26.6923 (Jun 15, 2022) |
| All-time low | $4.1763 (Jun 17, 2026) |
| 52-week high | $11.2759 |
| 52-week low | $4.1763 |
| Median price | $15.2666 |
| Average price | $14.7138 |
| Largest weekly change | -37.4% (Feb 22, 2023) |
| Weeks tracked | 195 |
| Tracking since | Feb 9, 2022 |
Generic Alternatives
The matcher finds 7 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 7 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 50% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ISOTRETINOIN 30 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 30 MG CAPSULE, manufactured by Upsher-Smith Laboratories LLC, is $4.1763 per EA (NDC 00245057301), effective Jul 1, 2026.
How has the price of ISOTRETINOIN 30 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for ISOTRETINOIN 30 MG CAPSULE has declined 84.4%. It has been tracked across 195 weekly CMS publications since Feb 9, 2022.
What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 30 MG CAPSULE?
Since Feb 9, 2022, the NADAC for ISOTRETINOIN 30 MG CAPSULE has ranged from a low of $4.1763 (Jun 17, 2026) to a high of $26.6923 (Jun 15, 2022), with a median of $15.2666 per EA.
Are there cheaper alternatives to ISOTRETINOIN 30 MG CAPSULE?
Yes. 7 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, ISOTRETINOIN 30 MG CAPSULE, is $2.0993 per EA — about 50% below ISOTRETINOIN 30 MG CAPSULE.
Who manufactures ISOTRETINOIN 30 MG CAPSULE?
ISOTRETINOIN 30 MG CAPSULE (NDC 00245057301) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.
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