Product Information
ADAPALENE-BNZYL PEROX 0.1-2.5% is a generic product labeled by Encube Ethicals, Inc., priced at $0.3682 per GM under NDC 21922005250. Its NADAC has been published 147 times since Dec 13, 2023.
FDA first approved this application on May 23, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1; 25 mg/g; mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922005250
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
ADAPALENE; BENZOYL PEROXIDEApproval Type
Generic (ANDA)
FDA Application
ANDA206164FDA Approved
5/23/2018
TE Code
AB
On Market Since
8/14/2023
Pharmacological Classes
Price Statistics
The NADAC for ADAPALENE-BNZYL PEROX 0.1-2.5% has been published 147 times since Dec 13, 2023, and over the history we have for it it has declined 43.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3682 per GM |
|---|---|
| All-time high | $0.7275 (Apr 10, 2024) |
| All-time low | $0.2823 (Jul 22, 2026) |
| 52-week high | $0.4191 |
| 52-week low | $0.2823 |
| Median price | $0.4474 |
| Average price | $0.4550 |
| Largest weekly change | -34.9% (Apr 17, 2024) |
| Weeks tracked | 147 |
| Tracking since | Dec 13, 2023 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5% market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Encube Ethicals, Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5% market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Retinoid class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ADAPALENE-BNZYL PEROX 0.1-2.5%?
The current National Average Drug Acquisition Cost (NADAC) for ADAPALENE-BNZYL PEROX 0.1-2.5%, manufactured by Encube Ethicals, Inc., is $0.3682 per GM (NDC 21922005250), effective Sep 30, 2026.
How has the price of ADAPALENE-BNZYL PEROX 0.1-2.5% changed over time?
Over the history we have for it, the NADAC for ADAPALENE-BNZYL PEROX 0.1-2.5% has declined 43.5%. It has been tracked across 147 weekly CMS publications since Dec 13, 2023.
What are the highest and lowest recorded NADAC prices for ADAPALENE-BNZYL PEROX 0.1-2.5%?
Since Dec 13, 2023, the NADAC for ADAPALENE-BNZYL PEROX 0.1-2.5% has ranged from a low of $0.2823 (Jul 22, 2026) to a high of $0.7275 (Apr 10, 2024), with a median of $0.4474 per GM.
Are there cheaper alternatives to ADAPALENE-BNZYL PEROX 0.1-2.5%?
No other NADAC-published product currently shares the active ingredient and strength of ADAPALENE-BNZYL PEROX 0.1-2.5% in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ADAPALENE-BNZYL PEROX 0.1-2.5%?
ADAPALENE-BNZYL PEROX 0.1-2.5% (NDC 21922005250) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.