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Product Information

ADAPALENE-BNZYL PEROX 0.1-2.5% is a generic product labeled by Encube Ethicals, Inc., priced at $0.3288 per GM under NDC 21922005250. Its NADAC has been published 141 times since Dec 13, 2023.

FDA first approved this application on May 23, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ADAPALENE-BNZYL PEROX 0.1-2.5%

Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5%
$0.3288per GM

Strength

1; 25 mg/g; mg/g

NDC

21922005250

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

ADAPALENE; BENZOYL PEROXIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA206164

FDA Approved

5/23/2018

TE Code

AB

On Market Since

8/14/2023

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for ADAPALENE-BNZYL PEROX 0.1-2.5% has been published 141 times since Dec 13, 2023, and over the history we have for it it has declined 49.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3288 per GM
All-time high$0.7275 (Apr 10, 2024)
All-time low$0.2823 (Jul 22, 2026)
52-week high$0.4445
52-week low$0.2823
Median price$0.4549
Average price$0.4598
Largest weekly change-34.9% (Apr 17, 2024)
Weeks tracked141
Tracking sinceDec 13, 2023

Price History

1W

+16.5%

1M

+16.5%

3M

+11.5%

6M

+9.5%

1Y

-26.0%

3Y

N/A

5Y

N/A

All

-49.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5% market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Related Drugs

Same classification

ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
45802084601•Padagis Israel Pharmaceuticals Ltd
$0.3288
per GM
ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
51672136403•Sun Pharmaceutical Industries Inc.
$0.3288
per GM
ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
68462030147•Glenmark Pharmaceuticals Inc., USA
$0.3288
per GM
ADAPALENE 0.1% GEL
Generic
00536141226•Rugby Laboratories
$0.3380
per GM
ADAPALENE 0.1% GEL
Generic
51672215006•Sun Pharmaceutical Industries Inc.
$0.3380
per GM
ADAPALENE 0.1% GEL
Generic
00536141220•Rugby Laboratories
$0.4670
per GM
GNP ADAPALENE 0.1% GEL
Generic
46122076836•AmerisourceBergen
$0.4670
per GM
ADAPALENE 0.1% GEL
Generic
51672215001•Sun Pharmaceutical Industries Inc.
$0.4670
per GM
TRETINOIN 0.025% CREAM
Generic
00378808245•Mylan Pharmaceuticals Inc.
$0.4684
per GM
TRETINOIN 0.025% CREAM
Generic
00472011745•Actavis Pharma, Inc.
$0.4684
per GM

Frequently asked questions

What is the NADAC price of ADAPALENE-BNZYL PEROX 0.1-2.5%?

The current National Average Drug Acquisition Cost (NADAC) for ADAPALENE-BNZYL PEROX 0.1-2.5%, manufactured by Encube Ethicals, Inc., is $0.3288 per GM (NDC 21922005250), effective Aug 19, 2026.

How has the price of ADAPALENE-BNZYL PEROX 0.1-2.5% changed over time?

Over the history we have for it, the NADAC for ADAPALENE-BNZYL PEROX 0.1-2.5% has declined 49.6%. It has been tracked across 141 weekly CMS publications since Dec 13, 2023.

What are the highest and lowest recorded NADAC prices for ADAPALENE-BNZYL PEROX 0.1-2.5%?

Since Dec 13, 2023, the NADAC for ADAPALENE-BNZYL PEROX 0.1-2.5% has ranged from a low of $0.2823 (Jul 22, 2026) to a high of $0.7275 (Apr 10, 2024), with a median of $0.4549 per GM.

Are there cheaper alternatives to ADAPALENE-BNZYL PEROX 0.1-2.5%?

No other NADAC-published product currently shares the active ingredient and strength of ADAPALENE-BNZYL PEROX 0.1-2.5% in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ADAPALENE-BNZYL PEROX 0.1-2.5%?

ADAPALENE-BNZYL PEROX 0.1-2.5% (NDC 21922005250) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.