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Product Information

ADAPALENE 0.1% GEL is a generic product labeled by Rugby Laboratories, priced at $0.4670 per GM under NDC 00536141220. Its NADAC has been published 105 times since Aug 21, 2024.

FDA first approved this application on Jan 14, 2022.

ADAPALENE 0.1% GEL

ADAPALENE
$0.4670per GM
OTC

Strength

1 mg/g

Manufacturer

Rugby Laboratories

NDC

00536141220

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

ADAPALENE

Approval Type

Generic (ANDA)

FDA Application

ANDA215940

FDA Approved

1/14/2022

On Market Since

2/20/2024

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for ADAPALENE 0.1% GEL has been published 105 times since Aug 21, 2024, and over the history we have for it it has declined 9.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4670 per GM
All-time high$0.5204 (Jan 15, 2025)
All-time low$0.4317 (Apr 22, 2026)
52-week high$0.4936
52-week low$0.4317
Median price$0.4762
Average price$0.4778
Largest weekly change-4.7% (Feb 18, 2026)
Weeks tracked105
Tracking sinceAug 21, 2024

Price History

1W

+1.3%

1M

+1.3%

3M

+5.3%

6M

+4.4%

1Y

-2.1%

3Y

N/A

5Y

N/A

All

-9.3%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 28% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 28%

1 alternative • Same active ingredient

ADAPALENE 0.1% GEL
Generic
00536141226•Rugby Laboratories
$0.3380
Save 28%

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51672136403•Sun Pharmaceutical Industries Inc.
$0.3288
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68462030147•Glenmark Pharmaceuticals Inc., USA
$0.3288
per GM
ADAPALENE 0.1% GEL
Generic
51672215006•Sun Pharmaceutical Industries Inc.
$0.3380
per GM
GNP ADAPALENE 0.1% GEL
Generic
46122076836•AmerisourceBergen
$0.4670
per GM
ADAPALENE 0.1% GEL
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51672215001•Sun Pharmaceutical Industries Inc.
$0.4670
per GM
TRETINOIN 0.025% CREAM
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00378808245•Mylan Pharmaceuticals Inc.
$0.4684
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00472011745•Actavis Pharma, Inc.
$0.4684
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TRETINOIN 0.025% CREAM
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00574222545•Padagis US LLC
$0.4684
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Frequently asked questions

What is the NADAC price of ADAPALENE 0.1% GEL?

The current National Average Drug Acquisition Cost (NADAC) for ADAPALENE 0.1% GEL, manufactured by Rugby Laboratories, is $0.4670 per GM (NDC 00536141220), effective Aug 19, 2026.

How has the price of ADAPALENE 0.1% GEL changed over time?

Over the history we have for it, the NADAC for ADAPALENE 0.1% GEL has declined 9.3%. It has been tracked across 105 weekly CMS publications since Aug 21, 2024.

What are the highest and lowest recorded NADAC prices for ADAPALENE 0.1% GEL?

Since Aug 21, 2024, the NADAC for ADAPALENE 0.1% GEL has ranged from a low of $0.4317 (Apr 22, 2026) to a high of $0.5204 (Jan 15, 2025), with a median of $0.4762 per GM.

Are there cheaper alternatives to ADAPALENE 0.1% GEL?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ADAPALENE 0.1% GEL, is $0.3380 per GM — about 28% below ADAPALENE 0.1% GEL.

Who manufactures ADAPALENE 0.1% GEL?

ADAPALENE 0.1% GEL (NDC 00536141220) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.