Product Information
TRETINOIN 0.025% CREAM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.4851 per GM under NDC 00378808245. Its NADAC has been published 364 times since Jul 10, 2019.
Strength
.25 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378808245
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA019049On Market Since
4/3/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% CREAM has been published 364 times since Jul 10, 2019, and over the history we have for it it has declined 74.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4851 per GM |
|---|---|
| All-time high | $2.3709 (Sep 16, 2020) |
| All-time low | $0.4851 (Jun 17, 2026) |
| 52-week high | $0.9756 |
| 52-week low | $0.4851 |
| Median price | $1.3453 |
| Average price | $1.3325 |
| Largest weekly change | +44.4% (Jun 19, 2024) |
| Weeks tracked | 364 |
| Tracking since | Jul 10, 2019 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $0.4851 per GM (NDC 00378808245), effective Jun 24, 2026.
How has the price of TRETINOIN 0.025% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% CREAM has declined 74.2%. It has been tracked across 364 weekly CMS publications since Jul 10, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% CREAM?
Since Jul 10, 2019, the NADAC for TRETINOIN 0.025% CREAM has ranged from a low of $0.4851 (Jun 17, 2026) to a high of $2.3709 (Sep 16, 2020), with a median of $1.3453 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% CREAM?
5 NADAC-published products share the same active ingredient, strength, and dosage form as TRETINOIN 0.025% CREAM, but none are currently priced below it.
Who manufactures TRETINOIN 0.025% CREAM?
TRETINOIN 0.025% CREAM (NDC 00378808245) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
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