Product Information
ADAPALENE 0.1% GEL is a generic product labeled by Rugby Laboratories, priced at $0.3365 per GM under NDC 00536141226. Its NADAC has been published 111 times since Aug 21, 2024.
FDA first approved this application on Jan 14, 2022.
Strength
1 mg/g
Manufacturer
Rugby LaboratoriesNDC
00536141226
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
ADAPALENEApproval Type
Generic (ANDA)
FDA Application
ANDA215940FDA Approved
1/14/2022
On Market Since
2/20/2024
Pharmacological Classes
Price Statistics
The NADAC for ADAPALENE 0.1% GEL has been published 111 times since Aug 21, 2024, and over the history we have for it it has declined 10.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3365 per GM |
|---|---|
| All-time high | $0.3942 (Dec 10, 2025) |
| All-time low | $0.3357 (Jun 18, 2025) |
| 52-week high | $0.3942 |
| 52-week low | $0.3365 |
| Median price | $0.3743 |
| Average price | $0.3653 |
| Largest weekly change | -11.0% (Jun 18, 2025) |
| Weeks tracked | 111 |
| Tracking since | Aug 21, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Rugby Laboratories manufacturer profile
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Drug market
ADAPALENE market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of ADAPALENE 0.1% GEL?
The current National Average Drug Acquisition Cost (NADAC) for ADAPALENE 0.1% GEL, manufactured by Rugby Laboratories, is $0.3365 per GM (NDC 00536141226), effective Sep 30, 2026.
How has the price of ADAPALENE 0.1% GEL changed over time?
Over the history we have for it, the NADAC for ADAPALENE 0.1% GEL has declined 10.2%. It has been tracked across 111 weekly CMS publications since Aug 21, 2024.
What are the highest and lowest recorded NADAC prices for ADAPALENE 0.1% GEL?
Since Aug 21, 2024, the NADAC for ADAPALENE 0.1% GEL has ranged from a low of $0.3357 (Jun 18, 2025) to a high of $0.3942 (Dec 10, 2025), with a median of $0.3743 per GM.
Are there cheaper alternatives to ADAPALENE 0.1% GEL?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ADAPALENE 0.1% GEL in a comparable dosage form, but none are currently priced below it.
Who manufactures ADAPALENE 0.1% GEL?
ADAPALENE 0.1% GEL (NDC 00536141226) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.