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Product Information

ADAPALENE 0.1% GEL is a generic product labeled by Rugby Laboratories, priced at $0.3380 per GM under NDC 00536141226. Its NADAC has been published 105 times since Aug 21, 2024.

FDA first approved this application on Jan 14, 2022.

ADAPALENE 0.1% GEL

ADAPALENE
$0.3380per GM
OTC

Strength

1 mg/g

Manufacturer

Rugby Laboratories

NDC

00536141226

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

ADAPALENE

Approval Type

Generic (ANDA)

FDA Application

ANDA215940

FDA Approved

1/14/2022

On Market Since

2/20/2024

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for ADAPALENE 0.1% GEL has been published 105 times since Aug 21, 2024, and over the history we have for it it has declined 9.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3380 per GM
All-time high$0.3942 (Dec 10, 2025)
All-time low$0.3357 (Jun 18, 2025)
52-week high$0.3942
52-week low$0.3380
Median price$0.3743
Average price$0.3669
Largest weekly change-11.0% (Jun 18, 2025)
Weeks tracked105
Tracking sinceAug 21, 2024

Price History

1W

-1.8%

1M

-1.8%

3M

-4.4%

6M

-3.0%

1Y

-7.2%

3Y

N/A

5Y

N/A

All

-9.8%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

ADAPALENE 0.1% GEL
Generic
00536141220•Rugby Laboratories
$0.4670
+38% more

Related Drugs

Same classification

ADAPALENE-BNZYL PEROX 0.1-2.5%
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$0.3288
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ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
45802084601•Padagis Israel Pharmaceuticals Ltd
$0.3288
per GM
ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
51672136403•Sun Pharmaceutical Industries Inc.
$0.3288
per GM
ADAPALENE-BNZYL PEROX 0.1-2.5%
Generic
68462030147•Glenmark Pharmaceuticals Inc., USA
$0.3288
per GM
ADAPALENE 0.1% GEL
Generic
51672215006•Sun Pharmaceutical Industries Inc.
$0.3380
per GM
GNP ADAPALENE 0.1% GEL
Generic
46122076836•AmerisourceBergen
$0.4670
per GM
ADAPALENE 0.1% GEL
Generic
51672215001•Sun Pharmaceutical Industries Inc.
$0.4670
per GM
TRETINOIN 0.025% CREAM
Generic
00378808245•Mylan Pharmaceuticals Inc.
$0.4684
per GM
TRETINOIN 0.025% CREAM
Generic
00472011745•Actavis Pharma, Inc.
$0.4684
per GM
TRETINOIN 0.025% CREAM
Generic
00574222545•Padagis US LLC
$0.4684
per GM

Frequently asked questions

What is the NADAC price of ADAPALENE 0.1% GEL?

The current National Average Drug Acquisition Cost (NADAC) for ADAPALENE 0.1% GEL, manufactured by Rugby Laboratories, is $0.3380 per GM (NDC 00536141226), effective Aug 19, 2026.

How has the price of ADAPALENE 0.1% GEL changed over time?

Over the history we have for it, the NADAC for ADAPALENE 0.1% GEL has declined 9.8%. It has been tracked across 105 weekly CMS publications since Aug 21, 2024.

What are the highest and lowest recorded NADAC prices for ADAPALENE 0.1% GEL?

Since Aug 21, 2024, the NADAC for ADAPALENE 0.1% GEL has ranged from a low of $0.3357 (Jun 18, 2025) to a high of $0.3942 (Dec 10, 2025), with a median of $0.3743 per GM.

Are there cheaper alternatives to ADAPALENE 0.1% GEL?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ADAPALENE 0.1% GEL in a comparable dosage form, but none are currently priced below it.

Who manufactures ADAPALENE 0.1% GEL?

ADAPALENE 0.1% GEL (NDC 00536141226) is labeled by Rugby Laboratories, and CMS classifies it as a generic product.