Product Information
RETIN-A 0.05% CREAM is a brand product labeled by Bausch Health US LLC, priced at $0.7914 per GM under NDC 00187516220. Its NADAC has been published 311 times since Aug 21, 2019.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Bausch Health US LLCNDC
00187516220
Classification
Brand
Dosage Form
CREAM
Route
TOPICAL
Effective Date
7/28/2025
Active Ingredients
TRETINOINApproval Type
New Drug (NDA)
FDA Application
NDA017522FDA Approved
Before 1982
TE Code
AB1
On Market Since
7/30/1974
Pharmacological Classes
Price Statistics
The NADAC for RETIN-A 0.05% CREAM has been published 311 times since Aug 21, 2019, and over the history we have for it it has declined 82.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7914 per GM |
|---|---|
| All-time high | $4.5160 (Oct 2, 2019) |
| All-time low | $0.7191 (Mar 20, 2024) |
| 52-week high | $0.7914 |
| 52-week low | $0.7914 |
| Median price | $3.7635 |
| Average price | $2.4595 |
| Largest weekly change | -81.1% (Feb 22, 2023) |
| Weeks tracked | 311 |
| Tracking since | Aug 21, 2019 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
+9.5%
5Y
-79.1%
All
-82.5%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of RETIN-A 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for RETIN-A 0.05% CREAM, manufactured by Bausch Health US LLC, is $0.7914 per GM (NDC 00187516220), effective Oct 1, 2025.
How has the price of RETIN-A 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for RETIN-A 0.05% CREAM has declined 82.5%. It has been tracked across 311 weekly CMS publications since Aug 21, 2019.
What are the highest and lowest recorded NADAC prices for RETIN-A 0.05% CREAM?
Since Aug 21, 2019, the NADAC for RETIN-A 0.05% CREAM has ranged from a low of $0.7191 (Mar 20, 2024) to a high of $4.5160 (Oct 2, 2019), with a median of $3.7635 per GM.
Are there cheaper alternatives to RETIN-A 0.05% CREAM?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RETIN-A 0.05% CREAM, is $0.7904 per GM — about 0% below RETIN-A 0.05% CREAM.
Who manufactures RETIN-A 0.05% CREAM?
RETIN-A 0.05% CREAM (NDC 00187516220) is labeled by Bausch Health US LLC, and CMS classifies it as a brand product.