Product Information
AKLIEF 0.005% CREAM is a brand product labeled by Galderma Laboratories, L.P., priced at $16.3623 per GM under NDC 00299593545. Its NADAC has been published 170 times since Feb 17, 2021.
FDA first approved this application on Oct 4, 2019.
Strength
50 ug/g
Manufacturer
Galderma Laboratories, L.P.NDC
00299593545
Classification
Brand
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
TRIFAROTENEApproval Type
New Drug (NDA)
FDA Application
NDA211527FDA Approved
10/4/2019
On Market Since
10/4/2019
Pharmacological Classes
Price Statistics
The NADAC for AKLIEF 0.005% CREAM has been published 170 times since Feb 17, 2021, and over the history we have for it it has risen 31.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $16.3623 per GM |
|---|---|
| All-time high | $16.3632 (Sep 16, 2026) |
| All-time low | $12.4198 (Feb 17, 2021) |
| 52-week high | $16.3632 |
| 52-week low | $15.6834 |
| Median price | $13.6607 |
| Average price | $14.4186 |
| Largest weekly change | +15.1% (May 21, 2025) |
| Weeks tracked | 170 |
| Tracking since | Feb 17, 2021 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the trifarotene market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
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Manufacturer
Galderma Laboratories, L.P. manufacturer profile
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Drug market
trifarotene market comparison
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Therapeutic class
Retinoid class view
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Trend hub
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of AKLIEF 0.005% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for AKLIEF 0.005% CREAM, manufactured by Galderma Laboratories, L.P., is $16.3623 per GM (NDC 00299593545), effective Sep 30, 2026.
How has the price of AKLIEF 0.005% CREAM changed over time?
Over the history we have for it, the NADAC for AKLIEF 0.005% CREAM has risen 31.7%. It has been tracked across 170 weekly CMS publications since Feb 17, 2021.
What are the highest and lowest recorded NADAC prices for AKLIEF 0.005% CREAM?
Since Feb 17, 2021, the NADAC for AKLIEF 0.005% CREAM has ranged from a low of $12.4198 (Feb 17, 2021) to a high of $16.3632 (Sep 16, 2026), with a median of $13.6607 per GM.
Are there cheaper alternatives to AKLIEF 0.005% CREAM?
No other NADAC-published product currently shares the active ingredient and strength of AKLIEF 0.005% CREAM in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures AKLIEF 0.005% CREAM?
AKLIEF 0.005% CREAM (NDC 00299593545) is labeled by Galderma Laboratories, L.P., and CMS classifies it as a brand product.