Product Information

AKLIEF 0.005% CREAM is a brand product labeled by Galderma Laboratories, L.P., priced at $16.2547 per GM under NDC 00299593545. Its NADAC has been published 156 times since Feb 17, 2021.

AKLIEF 0.005% CREAM

trifarotene
$16.2547per GM

Strength

50 ug/g

NDC

00299593545

Classification

Brand

Dosage Form

CREAM

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

TRIFAROTENE

Approval Type

New Drug (NDA)

FDA Application

NDA211527

On Market Since

10/4/2019

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for AKLIEF 0.005% CREAM has been published 156 times since Feb 17, 2021, and over the history we have for it it has risen 30.9%. The table below summarizes its recorded NADAC range and movement.

Current price$16.2547 per GM
All-time high$16.3397 (May 13, 2026)
All-time low$12.4198 (Feb 17, 2021)
52-week high$16.3397
52-week low$15.6834
Median price$13.6607
Average price$14.2466
Largest weekly change+15.1% (May 21, 2025)
Weeks tracked156
Tracking sinceFeb 17, 2021

Price History

1W

0.0%

1M

+0.3%

3M

-0.5%

6M

+3.5%

1Y

+3.4%

3Y

+19.0%

5Y

+24.8%

All

+30.9%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the trifarotene market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of AKLIEF 0.005% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for AKLIEF 0.005% CREAM, manufactured by Galderma Laboratories, L.P., is $16.2547 per GM (NDC 00299593545), effective Jun 24, 2026.

How has the price of AKLIEF 0.005% CREAM changed over time?

Over the history we have for it, the NADAC for AKLIEF 0.005% CREAM has risen 30.9%. It has been tracked across 156 weekly CMS publications since Feb 17, 2021.

What are the highest and lowest recorded NADAC prices for AKLIEF 0.005% CREAM?

Since Feb 17, 2021, the NADAC for AKLIEF 0.005% CREAM has ranged from a low of $12.4198 (Feb 17, 2021) to a high of $16.3397 (May 13, 2026), with a median of $13.6607 per GM.

Are there cheaper alternatives to AKLIEF 0.005% CREAM?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of AKLIEF 0.005% CREAM, so no direct lower-cost alternative is listed.

Who manufactures AKLIEF 0.005% CREAM?

AKLIEF 0.005% CREAM (NDC 00299593545) is labeled by Galderma Laboratories, L.P., and CMS classifies it as a brand product.