Product Information
TWYNEO 0.1%-3% CREAM PUMP is a brand product labeled by Galderma Laboratories, L.P., priced at $31.6568 per GM under NDC 00299594530. Its NADAC has been published 54 times since Nov 23, 2022.
FDA first approved this application on Jul 26, 2021.
Strength
30; 1 mg/g; mg/g
Manufacturer
Galderma Laboratories, L.P.NDC
00299594530
Classification
Brand
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/1/2026
Active Ingredients
BENZOYL PEROXIDE; TRETINOINApproval Type
New Drug (NDA)
FDA Application
NDA214902FDA Approved
7/26/2021
On Market Since
3/15/2022
Pharmacological Classes
Price Statistics
The NADAC for TWYNEO 0.1%-3% CREAM PUMP has been published 54 times since Nov 23, 2022, and over the history we have for it it has risen 133.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $31.6568 per GM |
|---|---|
| All-time high | $31.6568 (Sep 30, 2026) |
| All-time low | $13.5548 (Nov 23, 2022) |
| 52-week high | $31.6568 |
| 52-week low | $15.6574 |
| Median price | $15.6591 |
| Average price | $22.0992 |
| Largest weekly change | +91.7% (Apr 22, 2026) |
| Weeks tracked | 54 |
| Tracking since | Nov 23, 2022 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the tretinoin and benzoyl peroxide market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Galderma Laboratories, L.P. manufacturer profile
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Drug market
tretinoin and benzoyl peroxide market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TWYNEO 0.1%-3% CREAM PUMP?
The current National Average Drug Acquisition Cost (NADAC) for TWYNEO 0.1%-3% CREAM PUMP, manufactured by Galderma Laboratories, L.P., is $31.6568 per GM (NDC 00299594530), effective Sep 30, 2026.
How has the price of TWYNEO 0.1%-3% CREAM PUMP changed over time?
Over the history we have for it, the NADAC for TWYNEO 0.1%-3% CREAM PUMP has risen 133.5%. It has been tracked across 54 weekly CMS publications since Nov 23, 2022.
What are the highest and lowest recorded NADAC prices for TWYNEO 0.1%-3% CREAM PUMP?
Since Nov 23, 2022, the NADAC for TWYNEO 0.1%-3% CREAM PUMP has ranged from a low of $13.5548 (Nov 23, 2022) to a high of $31.6568 (Sep 30, 2026), with a median of $15.6591 per GM.
Are there cheaper alternatives to TWYNEO 0.1%-3% CREAM PUMP?
No other NADAC-published product currently shares the active ingredient and strength of TWYNEO 0.1%-3% CREAM PUMP in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures TWYNEO 0.1%-3% CREAM PUMP?
TWYNEO 0.1%-3% CREAM PUMP (NDC 00299594530) is labeled by Galderma Laboratories, L.P., and CMS classifies it as a brand product.