Product Information
ESTRADIOL 0.06 MG PATCH (1/WK) is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $12.2525 per EA under NDC 00378336199. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Feb 24, 2000. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.06 mg/d
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378336199
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA075182FDA Approved
2/24/2000
TE Code
AB2
On Market Since
8/9/2006
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.06 MG PATCH (1/WK) has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 7.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $12.2525 per EA |
|---|---|
| All-time high | $17.1377 (Jul 16, 2014) |
| All-time low | $8.2933 (Jul 17, 2024) |
| 52-week high | $13.5283 |
| 52-week low | $11.4879 |
| Median price | $13.8155 |
| Average price | $13.4474 |
| Largest weekly change | +50.1% (Jul 21, 2021) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the estradiol market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Mylan Pharmaceuticals Inc. manufacturer profile
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Drug market
estradiol market comparison
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Therapeutic class
Estrogen class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.06 MG PATCH (1/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.06 MG PATCH (1/WK), manufactured by Mylan Pharmaceuticals Inc., is $12.2525 per EA (NDC 00378336199), effective Sep 30, 2026.
How has the price of ESTRADIOL 0.06 MG PATCH (1/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.06 MG PATCH (1/WK) has declined 7.1%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.06 MG PATCH (1/WK)?
Since Nov 28, 2013, the NADAC for ESTRADIOL 0.06 MG PATCH (1/WK) has ranged from a low of $8.2933 (Jul 17, 2024) to a high of $17.1377 (Jul 16, 2014), with a median of $13.8155 per EA.
Are there cheaper alternatives to ESTRADIOL 0.06 MG PATCH (1/WK)?
No other NADAC-published product currently shares the active ingredient and strength of ESTRADIOL 0.06 MG PATCH (1/WK) in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ESTRADIOL 0.06 MG PATCH (1/WK)?
ESTRADIOL 0.06 MG PATCH (1/WK) (NDC 00378336199) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.