Product Information
ESTRADIOL 0.05 MG PATCH (2/WK) is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $7.7678 per EA under NDC 00378462126. Its NADAC has been published 391 times since Jan 2, 2019.
Strength
.05 mg/d
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378462126
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA206685On Market Since
11/1/2018
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.05 MG PATCH (2/WK) has been published 391 times since Jan 2, 2019, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.7678 per EA |
|---|---|
| All-time high | $9.2907 (Feb 16, 2022) |
| All-time low | $4.9914 (Nov 20, 2024) |
| 52-week high | $7.7678 |
| 52-week low | $6.8561 |
| Median price | $7.2756 |
| Average price | $7.2737 |
| Largest weekly change | +28.3% (Aug 21, 2024) |
| Weeks tracked | 391 |
| Tracking since | Jan 2, 2019 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.05 MG PATCH (2/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.05 MG PATCH (2/WK), manufactured by Mylan Pharmaceuticals Inc., is $7.7678 per EA (NDC 00378462126), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.05 MG PATCH (2/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.05 MG PATCH (2/WK) has held within roughly two percent of its current level. It has been tracked across 391 weekly CMS publications since Jan 2, 2019.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.05 MG PATCH (2/WK)?
Since Jan 2, 2019, the NADAC for ESTRADIOL 0.05 MG PATCH (2/WK) has ranged from a low of $4.9914 (Nov 20, 2024) to a high of $9.2907 (Feb 16, 2022), with a median of $7.2756 per EA.
Are there cheaper alternatives to ESTRADIOL 0.05 MG PATCH (2/WK)?
3 NADAC-published products share the same active ingredient, strength, and dosage form as ESTRADIOL 0.05 MG PATCH (2/WK), but none are currently priced below it.
Who manufactures ESTRADIOL 0.05 MG PATCH (2/WK)?
ESTRADIOL 0.05 MG PATCH (2/WK) (NDC 00378462126) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
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