Product Information
ISOTRETINOIN 10 MG CAPSULE is a generic product labeled by Upsher-Smith Laboratories LLC, priced at $1.8768 per EA under NDC 00832830130. Its NADAC has been published 155 times since Sep 6, 2023.
FDA first approved this application on Jan 19, 2012. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10 mg/1
Manufacturer
Upsher-Smith Laboratories LLCNDC
00832830130
Classification
Generic
Dosage Form
CAPSULE, LIQUID FILLED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ISOTRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA076485FDA Approved
1/19/2012
TE Code
AB1
On Market Since
5/1/2012
Pharmacological Classes
Price Statistics
The NADAC for ISOTRETINOIN 10 MG CAPSULE has been published 155 times since Sep 6, 2023, and over the history we have for it it has declined 2.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.8768 per EA |
|---|---|
| All-time high | $2.7340 (Jun 11, 2025) |
| All-time low | $1.3264 (Aug 21, 2024) |
| 52-week high | $2.2921 |
| 52-week low | $1.6125 |
| Median price | $1.8366 |
| Average price | $1.9058 |
| Largest weekly change | -32.9% (Apr 17, 2024) |
| Weeks tracked | 155 |
| Tracking since | Sep 6, 2023 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ISOTRETINOIN 10 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 10 MG CAPSULE, manufactured by Upsher-Smith Laboratories LLC, is $1.8768 per EA (NDC 00832830130), effective Aug 19, 2026.
How has the price of ISOTRETINOIN 10 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for ISOTRETINOIN 10 MG CAPSULE has declined 2.2%. It has been tracked across 155 weekly CMS publications since Sep 6, 2023.
What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 10 MG CAPSULE?
Since Sep 6, 2023, the NADAC for ISOTRETINOIN 10 MG CAPSULE has ranged from a low of $1.3264 (Aug 21, 2024) to a high of $2.7340 (Jun 11, 2025), with a median of $1.8366 per EA.
Are there cheaper alternatives to ISOTRETINOIN 10 MG CAPSULE?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ISOTRETINOIN 10 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures ISOTRETINOIN 10 MG CAPSULE?
ISOTRETINOIN 10 MG CAPSULE (NDC 00832830130) is labeled by Upsher-Smith Laboratories LLC, and CMS classifies it as a generic product.