Product Information
ESTRADIOL 0.1% (1.25 MG) GEL PK is a generic product labeled by Trigen Laboratories, LLC, priced at $1.1440 per GM under NDC 13811009432. Its NADAC has been published 123 times since Feb 21, 2024.
Strength
1.25 mg/1.25g
Manufacturer
Trigen Laboratories, LLCNDC
13811009432
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022038On Market Since
10/10/2022
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has been published 123 times since Feb 21, 2024, and over the history we have for it it has declined 54.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.1440 per GM |
|---|---|
| All-time high | $2.8779 (Jun 12, 2024) |
| All-time low | $1.1366 (Apr 22, 2026) |
| 52-week high | $1.7813 |
| 52-week low | $1.1366 |
| Median price | $1.5881 |
| Average price | $1.6645 |
| Largest weekly change | -30.5% (Jun 19, 2024) |
| Weeks tracked | 123 |
| Tracking since | Feb 21, 2024 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.1% (1.25 MG) GEL PK?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (1.25 MG) GEL PK, manufactured by Trigen Laboratories, LLC, is $1.1440 per GM (NDC 13811009432), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.1% (1.25 MG) GEL PK changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has declined 54.3%. It has been tracked across 123 weekly CMS publications since Feb 21, 2024.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (1.25 MG) GEL PK?
Since Feb 21, 2024, the NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has ranged from a low of $1.1366 (Apr 22, 2026) to a high of $2.8779 (Jun 12, 2024), with a median of $1.5881 per GM.
Are there cheaper alternatives to ESTRADIOL 0.1% (1.25 MG) GEL PK?
3 NADAC-published products share the same active ingredient, strength, and dosage form as ESTRADIOL 0.1% (1.25 MG) GEL PK, but none are currently priced below it.
Who manufactures ESTRADIOL 0.1% (1.25 MG) GEL PK?
ESTRADIOL 0.1% (1.25 MG) GEL PK (NDC 13811009432) is labeled by Trigen Laboratories, LLC, and CMS classifies it as a generic product.
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