Product Information
ESTRADIOL 0.1% (1.25 MG) GEL PK is a generic product labeled by NorthStar Rx LLC, priced at $0.8042 per GM under NDC 72603024530. Its NADAC has been published 125 times since Apr 3, 2024.
FDA first approved this application on Aug 24, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1.25 mg/1.25g
Manufacturer
NorthStar Rx LLCNDC
72603024530
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA217610FDA Approved
8/24/2023
TE Code
AB
On Market Since
12/18/2023
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has been published 125 times since Apr 3, 2024, and over the history we have for it it has declined 67.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.8042 per GM |
|---|---|
| All-time high | $2.8779 (Jun 12, 2024) |
| All-time low | $0.8042 (Aug 19, 2026) |
| 52-week high | $1.7813 |
| 52-week low | $0.8042 |
| Median price | $1.5635 |
| Average price | $1.5842 |
| Largest weekly change | -30.5% (Jun 19, 2024) |
| Weeks tracked | 125 |
| Tracking since | Apr 3, 2024 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.1% (1.25 MG) GEL PK?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (1.25 MG) GEL PK, manufactured by NorthStar Rx LLC, is $0.8042 per GM (NDC 72603024530), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.1% (1.25 MG) GEL PK changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has declined 67.9%. It has been tracked across 125 weekly CMS publications since Apr 3, 2024.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (1.25 MG) GEL PK?
Since Apr 3, 2024, the NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has ranged from a low of $0.8042 (Aug 19, 2026) to a high of $2.8779 (Jun 12, 2024), with a median of $1.5635 per GM.
Are there cheaper alternatives to ESTRADIOL 0.1% (1.25 MG) GEL PK?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.1% (1.25 MG) GEL PK in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.1% (1.25 MG) GEL PK?
ESTRADIOL 0.1% (1.25 MG) GEL PK (NDC 72603024530) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.