Product Information
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE is a generic product labeled by NorthStar Rx LLC, priced at $0.3355 per EA under NDC 16714017001. Its NADAC has been published 270 times since May 5, 2021.
FDA first approved this application on Jul 1, 2020. Its Orange Book therapeutic-equivalence code is AA.
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE
Butalbital, Acetaminophen, and CaffeineStrength
300; 50; 40 mg/1; mg/1; mg/1
Manufacturer
NorthStar Rx LLCNDC
16714017001
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
6/17/2026
Active Ingredients
ACETAMINOPHEN; BUTALBITAL; CAFFEINEApproval Type
Generic (ANDA)
FDA Application
ANDA213046FDA Approved
7/1/2020
TE Code
AA
On Market Since
7/1/2020
Pharmacological Classes
Price Statistics
The NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE has been published 270 times since May 5, 2021, and over the history we have for it it has declined 57.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3355 per EA |
|---|---|
| All-time high | $0.9560 (Apr 12, 2023) |
| All-time low | $0.3110 (Apr 22, 2026) |
| 52-week high | $0.4517 |
| 52-week low | $0.3110 |
| Median price | $0.5649 |
| Average price | $0.5493 |
| Largest weekly change | +34.5% (Jun 19, 2024) |
| Weeks tracked | 270 |
| Tracking since | May 5, 2021 |
1W
N/A
1M
N/A
3M
+1.2%
6M
+0.8%
1Y
-25.7%
3Y
-38.8%
5Y
-49.4%
All
-57.6%
Last surveyed Jul 1, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 6% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE, manufactured by NorthStar Rx LLC, is $0.3355 per EA (NDC 16714017001), effective Jul 1, 2026.
How has the price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE has declined 57.6%. It has been tracked across 270 weekly CMS publications since May 5, 2021.
What are the highest and lowest recorded NADAC prices for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE?
Since May 5, 2021, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE has ranged from a low of $0.3110 (Apr 22, 2026) to a high of $0.9560 (Apr 12, 2023), with a median of $0.5649 per EA.
Are there cheaper alternatives to BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE, is $0.3161 per EA — about 6% below BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE.
Who manufactures BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE?
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-300-40 MG CAPSULE (NDC 16714017001) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.