Product Information
AMITRIPTYLINE HCL 50 MG TAB is a generic product labeled by NorthStar Rx LLC, priced at $0.0904 per EA under NDC 16714025901. Its NADAC has been published 234 times since Mar 2, 2022.
FDA first approved this application on Oct 6, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
NorthStar Rx LLCNDC
16714025901
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
AMITRIPTYLINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA210086FDA Approved
10/6/2017
TE Code
AB
On Market Since
8/25/2021
Pharmacological Classes
Price Statistics
The NADAC for AMITRIPTYLINE HCL 50 MG TAB has been published 234 times since Mar 2, 2022, and over the history we have for it it has declined 43.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0904 per EA |
|---|---|
| All-time high | $0.1598 (Mar 16, 2022) |
| All-time low | $0.0677 (Nov 20, 2024) |
| 52-week high | $0.1019 |
| 52-week low | $0.0889 |
| Median price | $0.0931 |
| Average price | $0.0944 |
| Largest weekly change | +40.1% (Aug 21, 2024) |
| Weeks tracked | 234 |
| Tracking since | Mar 2, 2022 |
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of AMITRIPTYLINE HCL 50 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for AMITRIPTYLINE HCL 50 MG TAB, manufactured by NorthStar Rx LLC, is $0.0904 per EA (NDC 16714025901), effective Aug 19, 2026.
How has the price of AMITRIPTYLINE HCL 50 MG TAB changed over time?
Over the history we have for it, the NADAC for AMITRIPTYLINE HCL 50 MG TAB has declined 43.4%. It has been tracked across 234 weekly CMS publications since Mar 2, 2022.
What are the highest and lowest recorded NADAC prices for AMITRIPTYLINE HCL 50 MG TAB?
Since Mar 2, 2022, the NADAC for AMITRIPTYLINE HCL 50 MG TAB has ranged from a low of $0.0677 (Nov 20, 2024) to a high of $0.1598 (Mar 16, 2022), with a median of $0.0931 per EA.
Are there cheaper alternatives to AMITRIPTYLINE HCL 50 MG TAB?
12 manufacturers publish a NADAC-priced product with the same active ingredient and strength as AMITRIPTYLINE HCL 50 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures AMITRIPTYLINE HCL 50 MG TAB?
AMITRIPTYLINE HCL 50 MG TAB (NDC 16714025901) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.