Product Information
ACYCLOVIR 5% OINTMENT is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.5808 per GM under NDC 33342043915. Its NADAC has been published 151 times since Feb 23, 2022.
FDA first approved this application on May 19, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/g
Manufacturer
Macleods Pharmaceuticals LimitedNDC
33342043915
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
4/23/2025
Active Ingredients
ACYCLOVIRApproval Type
Generic (ANDA)
FDA Application
ANDA212444FDA Approved
5/19/2021
TE Code
AB
On Market Since
8/13/2018
Pharmacological Classes
Price Statistics
The NADAC for ACYCLOVIR 5% OINTMENT has been published 151 times since Feb 23, 2022, and over the history we have for it it has declined 39.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5808 per GM |
|---|---|
| All-time high | $1.3693 (Apr 13, 2022) |
| All-time low | $0.4269 (Nov 20, 2024) |
| Median price | $0.7527 |
| Average price | $0.7508 |
| Largest weekly change | +46.7% (Aug 17, 2022) |
| Weeks tracked | 151 |
| Tracking since | Feb 23, 2022 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
-28.8%
5Y
N/A
All
-39.8%
Last surveyed May 14, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 41% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ACYCLOVIR 5% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 5% OINTMENT, manufactured by Macleods Pharmaceuticals Limited, is $0.5808 per GM (NDC 33342043915), effective May 14, 2025.
How has the price of ACYCLOVIR 5% OINTMENT changed over time?
Over the history we have for it, the NADAC for ACYCLOVIR 5% OINTMENT has declined 39.8%. It has been tracked across 151 weekly CMS publications since Feb 23, 2022.
What are the highest and lowest recorded NADAC prices for ACYCLOVIR 5% OINTMENT?
Since Feb 23, 2022, the NADAC for ACYCLOVIR 5% OINTMENT has ranged from a low of $0.4269 (Nov 20, 2024) to a high of $1.3693 (Apr 13, 2022), with a median of $0.7527 per GM.
Are there cheaper alternatives to ACYCLOVIR 5% OINTMENT?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ACYCLOVIR 5% OINTMENT, is $0.3421 per GM — about 41% below ACYCLOVIR 5% OINTMENT.
Who manufactures ACYCLOVIR 5% OINTMENT?
ACYCLOVIR 5% OINTMENT (NDC 33342043915) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.