Product Information
BUPROPION HCL SR 150 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.0824 per EA under NDC 42806042505. Its NADAC has been published 67 times since May 14, 2025.
FDA first approved this application on Oct 16, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
150 mg/1
Manufacturer
Epic Pharma LLCNDC
42806042505
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA211347FDA Approved
10/16/2018
TE Code
AB1
On Market Since
9/18/2023
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL SR 150 MG TABLET has been published 67 times since May 14, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0824 per EA |
|---|---|
| All-time high | $0.0863 (Jul 16, 2025) |
| All-time low | $0.0805 (Oct 22, 2025) |
| 52-week high | $0.0852 |
| 52-week low | $0.0805 |
| Median price | $0.0831 |
| Average price | $0.0833 |
| Largest weekly change | -3.9% (Sep 17, 2025) |
| Weeks tracked | 67 |
| Tracking since | May 14, 2025 |
Generic Alternatives
The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 5% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPROPION HCL SR 150 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 150 MG TABLET, manufactured by Epic Pharma LLC, is $0.0824 per EA (NDC 42806042505), effective Aug 19, 2026.
How has the price of BUPROPION HCL SR 150 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL SR 150 MG TABLET has held within roughly two percent of its current level. It has been tracked across 67 weekly CMS publications since May 14, 2025.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 150 MG TABLET?
Since May 14, 2025, the NADAC for BUPROPION HCL SR 150 MG TABLET has ranged from a low of $0.0805 (Oct 22, 2025) to a high of $0.0863 (Jul 16, 2025), with a median of $0.0831 per EA.
Are there cheaper alternatives to BUPROPION HCL SR 150 MG TABLET?
Yes. 14 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL XL 150 MG TABLET, is $0.0779 per EA — about 5% below BUPROPION HCL SR 150 MG TABLET.
Who manufactures BUPROPION HCL SR 150 MG TABLET?
BUPROPION HCL SR 150 MG TABLET (NDC 42806042505) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.