Product Information

THEOPHYLLINE ER 400 MG TABLET is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $1.0151 per EA under NDC 42858070101. Its NADAC has been published 661 times since Nov 28, 2013.

FDA first approved this application on Sep 1, 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Theophylline market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

THEOPHYLLINE ER 400 MG TABLET

Theophylline
$1.0151per EA
High Outlier

Strength

400 mg/1

NDC

42858070101

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

THEOPHYLLINE ANHYDROUS

Approval Type

Generic (ANDA)

FDA Application

ANDA040086

FDA Approved

9/1/1982

TE Code

AB

On Market Since

2/2/2012

Pharmacological Classes

Price Statistics

The NADAC for THEOPHYLLINE ER 400 MG TABLET has been published 661 times since Nov 28, 2013, and over the history we have for it it has risen 11.4%. The table below summarizes its recorded NADAC range and movement.

Current price$1.0151 per EA
All-time high$1.0435 (Feb 12, 2014)
All-time low$0.4646 (Nov 22, 2023)
52-week high$1.0376
52-week low$0.8081
Median price$0.8260
Average price$0.8083
Largest weekly change+49.2% (Jan 17, 2024)
Weeks tracked661
Tracking sinceNov 28, 2013

Price History

1W

+1.7%

1M

+1.7%

3M

+7.2%

6M

+4.5%

1Y

+25.6%

3Y

+64.9%

5Y

+48.7%

All

+11.4%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of THEOPHYLLINE ER 400 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for THEOPHYLLINE ER 400 MG TABLET, manufactured by Rhodes Pharmaceuticals L.P., is $1.0151 per EA (NDC 42858070101), effective Aug 19, 2026.

How has the price of THEOPHYLLINE ER 400 MG TABLET changed over time?

Over the history we have for it, the NADAC for THEOPHYLLINE ER 400 MG TABLET has risen 11.4%. It has been tracked across 661 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for THEOPHYLLINE ER 400 MG TABLET?

Since Nov 28, 2013, the NADAC for THEOPHYLLINE ER 400 MG TABLET has ranged from a low of $0.4646 (Nov 22, 2023) to a high of $1.0435 (Feb 12, 2014), with a median of $0.8260 per EA.

Are there cheaper alternatives to THEOPHYLLINE ER 400 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as THEOPHYLLINE ER 400 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures THEOPHYLLINE ER 400 MG TABLET?

THEOPHYLLINE ER 400 MG TABLET (NDC 42858070101) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.