Product Information

BUPROPION HCL SR 100 MG TABLET is a generic product labeled by Dr. Reddy's Laboratories Inc., priced at $0.0687 per EA under NDC 43598075160. Its NADAC has been published 422 times since Jul 25, 2018.

FDA first approved this application on Mar 1, 2016. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL SR 100 MG TABLET

bupropion hydrochloride
$0.0687per EA

Strength

100 mg/1

NDC

43598075160

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA205794

FDA Approved

3/1/2016

TE Code

AB1

On Market Since

5/15/2018

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL SR 100 MG TABLET has been published 422 times since Jul 25, 2018, and over the history we have for it it has declined 56.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0687 per EA
All-time high$0.1809 (Nov 13, 2019)
All-time low$0.0639 (Oct 22, 2025)
52-week high$0.0812
52-week low$0.0639
Median price$0.1092
Average price$0.1202
Largest weekly change+30.2% (Jun 19, 2024)
Weeks tracked422
Tracking sinceJul 25, 2018

Price History

1W

+0.0%

1M

-8.7%

3M

-8.4%

6M

-3.0%

1Y

-25.5%

3Y

-31.3%

5Y

-48.7%

All

-56.9%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL SR 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 100 MG TABLET, manufactured by Dr. Reddy's Laboratories Inc., is $0.0687 per EA (NDC 43598075160), effective Aug 19, 2026.

How has the price of BUPROPION HCL SR 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL SR 100 MG TABLET has declined 56.9%. It has been tracked across 422 weekly CMS publications since Jul 25, 2018.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 100 MG TABLET?

Since Jul 25, 2018, the NADAC for BUPROPION HCL SR 100 MG TABLET has ranged from a low of $0.0639 (Oct 22, 2025) to a high of $0.1809 (Nov 13, 2019), with a median of $0.1092 per EA.

Are there cheaper alternatives to BUPROPION HCL SR 100 MG TABLET?

7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 100 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL SR 100 MG TABLET?

BUPROPION HCL SR 100 MG TABLET (NDC 43598075160) is labeled by Dr. Reddy's Laboratories Inc., and CMS classifies it as a generic product.