Product Information
BUPROPION HCL SR 100 MG TABLET is a generic product labeled by Dr. Reddy's Laboratories Inc., priced at $0.0679 per EA under NDC 43598075105. Its NADAC has been published 418 times since Oct 3, 2018.
FDA first approved this application on Mar 1, 2016. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Dr. Reddy's Laboratories Inc.NDC
43598075105
Classification
Generic
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA205794FDA Approved
3/1/2016
TE Code
AB1
On Market Since
5/15/2018
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL SR 100 MG TABLET has been published 418 times since Oct 3, 2018, and over the history we have for it it has declined 62.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0679 per EA |
|---|---|
| All-time high | $0.1809 (Nov 13, 2019) |
| All-time low | $0.0639 (Oct 22, 2025) |
| 52-week high | $0.0752 |
| 52-week low | $0.0639 |
| Median price | $0.1082 |
| Average price | $0.1184 |
| Largest weekly change | +30.2% (Jun 19, 2024) |
| Weeks tracked | 418 |
| Tracking since | Oct 3, 2018 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Dr. Reddy's Laboratories Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
bupropion hydrochloride market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Aminoketone class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPROPION HCL SR 100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 100 MG TABLET, manufactured by Dr. Reddy's Laboratories Inc., is $0.0679 per EA (NDC 43598075105), effective Sep 30, 2026.
How has the price of BUPROPION HCL SR 100 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL SR 100 MG TABLET has declined 62.3%. It has been tracked across 418 weekly CMS publications since Oct 3, 2018.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 100 MG TABLET?
Since Oct 3, 2018, the NADAC for BUPROPION HCL SR 100 MG TABLET has ranged from a low of $0.0639 (Oct 22, 2025) to a high of $0.1809 (Nov 13, 2019), with a median of $0.1082 per EA.
Are there cheaper alternatives to BUPROPION HCL SR 100 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 100 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPROPION HCL SR 100 MG TABLET?
BUPROPION HCL SR 100 MG TABLET (NDC 43598075105) is labeled by Dr. Reddy's Laboratories Inc., and CMS classifies it as a generic product.