Product Information

BUPROPION HCL SR 100 MG TABLET is a generic product labeled by American Health Packaging, priced at $0.0687 per EA under NDC 68084069701. Its NADAC has been published 590 times since May 6, 2015.

FDA first approved this application on Mar 24, 2009. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL SR 100 MG TABLET

bupropion hydrochloride
$0.0687per EA

Strength

100 mg/1

NDC

68084069701

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA079095

FDA Approved

3/24/2009

TE Code

AB1

On Market Since

4/2/2015

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL SR 100 MG TABLET has been published 590 times since May 6, 2015, and over the history we have for it it has declined 73.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0687 per EA
All-time high$0.2608 (Aug 12, 2015)
All-time low$0.0639 (Oct 22, 2025)
52-week high$0.0812
52-week low$0.0639
Median price$0.1484
Average price$0.1438
Largest weekly change+30.2% (Jun 19, 2024)
Weeks tracked590
Tracking sinceMay 6, 2015

Price History

1W

+0.0%

1M

-8.7%

3M

-8.4%

6M

-3.0%

1Y

-15.4%

3Y

-31.3%

5Y

-48.7%

All

-73.6%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL SR 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 100 MG TABLET, manufactured by American Health Packaging, is $0.0687 per EA (NDC 68084069701), effective Aug 19, 2026.

How has the price of BUPROPION HCL SR 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL SR 100 MG TABLET has declined 73.6%. It has been tracked across 590 weekly CMS publications since May 6, 2015.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 100 MG TABLET?

Since May 6, 2015, the NADAC for BUPROPION HCL SR 100 MG TABLET has ranged from a low of $0.0639 (Oct 22, 2025) to a high of $0.2608 (Aug 12, 2015), with a median of $0.1484 per EA.

Are there cheaper alternatives to BUPROPION HCL SR 100 MG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 100 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL SR 100 MG TABLET?

BUPROPION HCL SR 100 MG TABLET (NDC 68084069701) is labeled by American Health Packaging, and CMS classifies it as a generic product.