Product Information

BUPROPION HCL SR 200 MG TABLET is a generic product labeled by ScieGen Pharmaceuticals, Inc., priced at $0.1087 per EA under NDC 50228017660. Its NADAC has been published 315 times since Aug 12, 2020.

FDA first approved this application on Mar 1, 2016. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL SR 200 MG TABLET

bupropion hydrochloride
$0.1087per EA

Strength

200 mg/1

NDC

50228017660

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA205794

FDA Approved

3/1/2016

TE Code

AB1

On Market Since

4/20/2018

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL SR 200 MG TABLET has been published 315 times since Aug 12, 2020, and over the history we have for it it has declined 52.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1087 per EA
All-time high$0.2386 (Dec 16, 2020)
All-time low$0.1002 (Nov 19, 2025)
52-week high$0.1380
52-week low$0.1002
Median price$0.1460
Average price$0.1518
Largest weekly change+39.8% (May 19, 2021)
Weeks tracked315
Tracking sinceAug 12, 2020

Price History

1W

-2.0%

1M

-2.0%

3M

+0.3%

6M

-5.4%

1Y

-21.2%

3Y

-22.7%

5Y

-40.1%

All

-52.8%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL SR 200 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 200 MG TABLET, manufactured by ScieGen Pharmaceuticals, Inc., is $0.1087 per EA (NDC 50228017660), effective Aug 19, 2026.

How has the price of BUPROPION HCL SR 200 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL SR 200 MG TABLET has declined 52.8%. It has been tracked across 315 weekly CMS publications since Aug 12, 2020.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 200 MG TABLET?

Since Aug 12, 2020, the NADAC for BUPROPION HCL SR 200 MG TABLET has ranged from a low of $0.1002 (Nov 19, 2025) to a high of $0.2386 (Dec 16, 2020), with a median of $0.1460 per EA.

Are there cheaper alternatives to BUPROPION HCL SR 200 MG TABLET?

7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 200 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL SR 200 MG TABLET?

BUPROPION HCL SR 200 MG TABLET (NDC 50228017660) is labeled by ScieGen Pharmaceuticals, Inc., and CMS classifies it as a generic product.