Product Information

BUPROPION HCL SR 200 MG TABLET is a generic product labeled by ScieGen Pharmaceuticals, Inc., priced at $0.1036 per EA under NDC 50228017660. Its NADAC has been published 321 times since Aug 12, 2020.

FDA first approved this application on Mar 1, 2016. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL SR 200 MG TABLET

bupropion hydrochloride
$0.1036per EA

Strength

200 mg/1

NDC

50228017660

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

9/23/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA205794

FDA Approved

3/1/2016

TE Code

AB1

On Market Since

4/20/2018

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL SR 200 MG TABLET has been published 321 times since Aug 12, 2020, and over the history we have for it it has declined 55.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1036 per EA
All-time high$0.2386 (Dec 16, 2020)
All-time low$0.1002 (Nov 19, 2025)
52-week high$0.1205
52-week low$0.1002
Median price$0.1460
Average price$0.1509
Largest weekly change+39.8% (May 19, 2021)
Weeks tracked321
Tracking sinceAug 12, 2020

Price History

1W

0.0%

1M

-4.7%

3M

-6.6%

6M

-6.7%

1Y

-14.0%

3Y

-37.2%

5Y

-46.1%

All

-55.0%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of BUPROPION HCL SR 200 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 200 MG TABLET, manufactured by ScieGen Pharmaceuticals, Inc., is $0.1036 per EA (NDC 50228017660), effective Sep 30, 2026.

How has the price of BUPROPION HCL SR 200 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL SR 200 MG TABLET has declined 55.0%. It has been tracked across 321 weekly CMS publications since Aug 12, 2020.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 200 MG TABLET?

Since Aug 12, 2020, the NADAC for BUPROPION HCL SR 200 MG TABLET has ranged from a low of $0.1002 (Nov 19, 2025) to a high of $0.2386 (Dec 16, 2020), with a median of $0.1460 per EA.

Are there cheaper alternatives to BUPROPION HCL SR 200 MG TABLET?

7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 200 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL SR 200 MG TABLET?

BUPROPION HCL SR 200 MG TABLET (NDC 50228017660) is labeled by ScieGen Pharmaceuticals, Inc., and CMS classifies it as a generic product.