Product Information
BUPROPION HCL XL 150 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.0787 per EA under NDC 00904750561. Its NADAC has been published 74 times since Mar 26, 2025.
FDA first approved this application on Apr 6, 2017. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
150 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904750561
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA090693FDA Approved
4/6/2017
TE Code
AB3
On Market Since
11/25/2024
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL XL 150 MG TABLET has been published 74 times since Mar 26, 2025, and over the history we have for it it has declined 25.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0787 per EA |
|---|---|
| All-time high | $0.1059 (Apr 16, 2025) |
| All-time low | $0.0770 (Apr 22, 2026) |
| 52-week high | $0.1015 |
| 52-week low | $0.0770 |
| Median price | $0.0943 |
| Average price | $0.0913 |
| Largest weekly change | -8.4% (Feb 18, 2026) |
| Weeks tracked | 74 |
| Tracking since | Mar 26, 2025 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPROPION HCL XL 150 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 150 MG TABLET, manufactured by Major Pharmaceuticals, is $0.0787 per EA (NDC 00904750561), effective Aug 19, 2026.
How has the price of BUPROPION HCL XL 150 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL XL 150 MG TABLET has declined 25.7%. It has been tracked across 74 weekly CMS publications since Mar 26, 2025.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 150 MG TABLET?
Since Mar 26, 2025, the NADAC for BUPROPION HCL XL 150 MG TABLET has ranged from a low of $0.0770 (Apr 22, 2026) to a high of $0.1059 (Apr 16, 2025), with a median of $0.0943 per EA.
Are there cheaper alternatives to BUPROPION HCL XL 150 MG TABLET?
11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL XL 150 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPROPION HCL XL 150 MG TABLET?
BUPROPION HCL XL 150 MG TABLET (NDC 00904750561) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.