Product Information
BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM is a generic product labeled by Ingenus Pharmaceuticals LLC, priced at $1.3855 per EA under NDC 50742039730. Its NADAC has been published 66 times since Jul 2, 2025.
FDA first approved this application on Jun 2, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2; .5 mg/1; mg/1
Manufacturer
Ingenus Pharmaceuticals LLCNDC
50742039730
Classification
Generic
Dosage Form
FILM
Route
BUCCAL; SUBLINGUAL
Effective Date
9/23/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDE; NALOXONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA212756FDA Approved
6/2/2022
TE Code
AB
On Market Since
8/29/2023
Pharmacological Classes
Price Statistics
The NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM has been published 66 times since Jul 2, 2025, and over the history we have for it it has declined 25.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3855 per EA |
|---|---|
| All-time high | $1.9156 (Sep 10, 2025) |
| All-time low | $1.2800 (Jun 17, 2026) |
| 52-week high | $1.9127 |
| 52-week low | $1.2800 |
| Median price | $1.3785 |
| Average price | $1.5357 |
| Largest weekly change | -14.4% (Jan 21, 2026) |
| Weeks tracked | 66 |
| Tracking since | Jul 2, 2025 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the buprenorphine and naloxone market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
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Manufacturer
Ingenus Pharmaceuticals LLC manufacturer profile
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Drug market
buprenorphine and naloxone market comparison
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Therapeutic class
Opioid Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM?
The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM, manufactured by Ingenus Pharmaceuticals LLC, is $1.3855 per EA (NDC 50742039730), effective Sep 30, 2026.
How has the price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM changed over time?
Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM has declined 25.5%. It has been tracked across 66 weekly CMS publications since Jul 2, 2025.
What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM?
Since Jul 2, 2025, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM has ranged from a low of $1.2800 (Jun 17, 2026) to a high of $1.9156 (Sep 10, 2025), with a median of $1.3785 per EA.
Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM?
No other NADAC-published product currently shares the active ingredient and strength of BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM?
BUPRENORPHINE-NALOXONE 2-0.5 MG SL FILM (NDC 50742039730) is labeled by Ingenus Pharmaceuticals LLC, and CMS classifies it as a generic product.