Product Information
BUPRENORPHINE-NALOXONE 4-1 MG SL FILM is a generic product labeled by Ingenus Pharmaceuticals LLC, priced at $2.5307 per EA under NDC 50742039830. Its NADAC has been published 60 times since Jul 2, 2025.
FDA first approved this application on Jun 2, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
4; 1 mg/1; mg/1
Manufacturer
Ingenus Pharmaceuticals LLCNDC
50742039830
Classification
Generic
Dosage Form
FILM
Route
BUCCAL; SUBLINGUAL
Effective Date
8/19/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDE; NALOXONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA212756FDA Approved
6/2/2022
TE Code
AB
On Market Since
8/29/2023
Pharmacological Classes
Price Statistics
The NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has been published 60 times since Jul 2, 2025, and over the history we have for it it has declined 26.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5307 per EA |
|---|---|
| All-time high | $3.5744 (Sep 10, 2025) |
| All-time low | $2.2214 (Mar 18, 2026) |
| 52-week high | $3.5744 |
| 52-week low | $2.2214 |
| Median price | $2.4496 |
| Average price | $2.7817 |
| Largest weekly change | -14.5% (Jan 21, 2026) |
| Weeks tracked | 60 |
| Tracking since | Jul 2, 2025 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the buprenorphine and naloxone market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?
The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM, manufactured by Ingenus Pharmaceuticals LLC, is $2.5307 per EA (NDC 50742039830), effective Aug 19, 2026.
How has the price of BUPRENORPHINE-NALOXONE 4-1 MG SL FILM changed over time?
Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has declined 26.5%. It has been tracked across 60 weekly CMS publications since Jul 2, 2025.
What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?
Since Jul 2, 2025, the NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has ranged from a low of $2.2214 (Mar 18, 2026) to a high of $3.5744 (Sep 10, 2025), with a median of $2.4496 per EA.
Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?
No other NADAC-published product currently shares the active ingredient and strength of BUPRENORPHINE-NALOXONE 4-1 MG SL FILM in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?
BUPRENORPHINE-NALOXONE 4-1 MG SL FILM (NDC 50742039830) is labeled by Ingenus Pharmaceuticals LLC, and CMS classifies it as a generic product.