Product Information
ESTRADIOL-NORETH 0.5-0.1 MG TB is a generic product labeled by Ingenus Pharmaceuticals LLC, priced at $0.8020 per EA under NDC 50742065828. Its NADAC has been published 361 times since Nov 6, 2019.
FDA first approved this application on Apr 3, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5; .1 mg/1; mg/1
Manufacturer
Ingenus Pharmaceuticals LLCNDC
50742065828
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOL; NORETHINDRONE ACETATEApproval Type
Generic (ANDA)
FDA Application
ANDA210612FDA Approved
4/3/2019
TE Code
AB
On Market Since
4/3/2019
Price Statistics
The NADAC for ESTRADIOL-NORETH 0.5-0.1 MG TB has been published 361 times since Nov 6, 2019, and over the history we have for it it has declined 67.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.8020 per EA |
|---|---|
| All-time high | $2.6051 (Dec 11, 2019) |
| All-time low | $0.4048 (Nov 20, 2024) |
| 52-week high | $0.9671 |
| 52-week low | $0.6778 |
| Median price | $0.8836 |
| Average price | $1.2207 |
| Largest weekly change | +61.5% (Aug 21, 2024) |
| Weeks tracked | 361 |
| Tracking since | Nov 6, 2019 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Ingenus Pharmaceuticals LLC manufacturer profile
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Drug market
Estradiol and Norethindrone Acetate market comparison
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Therapeutic class
Estrogen class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ESTRADIOL-NORETH 0.5-0.1 MG TB?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL-NORETH 0.5-0.1 MG TB, manufactured by Ingenus Pharmaceuticals LLC, is $0.8020 per EA (NDC 50742065828), effective Sep 30, 2026.
How has the price of ESTRADIOL-NORETH 0.5-0.1 MG TB changed over time?
Over the history we have for it, the NADAC for ESTRADIOL-NORETH 0.5-0.1 MG TB has declined 67.6%. It has been tracked across 361 weekly CMS publications since Nov 6, 2019.
What are the highest and lowest recorded NADAC prices for ESTRADIOL-NORETH 0.5-0.1 MG TB?
Since Nov 6, 2019, the NADAC for ESTRADIOL-NORETH 0.5-0.1 MG TB has ranged from a low of $0.4048 (Nov 20, 2024) to a high of $2.6051 (Dec 11, 2019), with a median of $0.8836 per EA.
Are there cheaper alternatives to ESTRADIOL-NORETH 0.5-0.1 MG TB?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL-NORETH 0.5-0.1 MG TB in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL-NORETH 0.5-0.1 MG TB?
ESTRADIOL-NORETH 0.5-0.1 MG TB (NDC 50742065828) is labeled by Ingenus Pharmaceuticals LLC, and CMS classifies it as a generic product.