Product Information
CHLORTHALIDONE 50 MG TABLET is a generic product labeled by TAGI Pharma Inc., priced at $0.1357 per EA under NDC 51224011850. Its NADAC has been published 156 times since Nov 30, 2022.
FDA first approved this application on Feb 24, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
TAGI Pharma Inc.NDC
51224011850
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
11/19/2025
Active Ingredients
CHLORTHALIDONEApproval Type
Generic (ANDA)
FDA Application
ANDA212875FDA Approved
2/24/2022
TE Code
AB
On Market Since
8/5/2022
Pharmacological Classes
Price Statistics
The NADAC for CHLORTHALIDONE 50 MG TABLET has been published 156 times since Nov 30, 2022, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1357 per EA |
|---|---|
| All-time high | $0.1968 (Mar 15, 2023) |
| All-time low | $0.0987 (May 22, 2024) |
| 52-week high | $0.1357 |
| 52-week low | $0.1259 |
| Median price | $0.1340 |
| Average price | $0.1373 |
| Largest weekly change | +39.8% (Aug 21, 2024) |
| Weeks tracked | 156 |
| Tracking since | Nov 30, 2022 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+2.2%
3Y
+4.4%
5Y
N/A
All
+0.7%
Last surveyed Nov 19, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 11% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CHLORTHALIDONE 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for CHLORTHALIDONE 50 MG TABLET, manufactured by TAGI Pharma Inc., is $0.1357 per EA (NDC 51224011850), effective Nov 19, 2025.
How has the price of CHLORTHALIDONE 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for CHLORTHALIDONE 50 MG TABLET has held within roughly two percent of its current level. It has been tracked across 156 weekly CMS publications since Nov 30, 2022.
What are the highest and lowest recorded NADAC prices for CHLORTHALIDONE 50 MG TABLET?
Since Nov 30, 2022, the NADAC for CHLORTHALIDONE 50 MG TABLET has ranged from a low of $0.0987 (May 22, 2024) to a high of $0.1968 (Mar 15, 2023), with a median of $0.1340 per EA.
Are there cheaper alternatives to CHLORTHALIDONE 50 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CHLORTHALIDONE 50 MG TABLET, is $0.1210 per EA — about 11% below CHLORTHALIDONE 50 MG TABLET.
Who manufactures CHLORTHALIDONE 50 MG TABLET?
CHLORTHALIDONE 50 MG TABLET (NDC 51224011850) is labeled by TAGI Pharma Inc., and CMS classifies it as a generic product.