Product Information

BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE is a generic product labeled by Mayne Pharma, priced at $2.0089 per EA under NDC 51862017901. Its NADAC has been published 633 times since Nov 28, 2013.

FDA first approved this application on Mar 17, 1986. Its Orange Book therapeutic-equivalence code is AA.

BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE

butalbital, acetaminophen and caffeine
$2.0089per EA

Strength

325; 50; 40 mg/1; mg/1; mg/1

Manufacturer

Mayne Pharma

NDC

51862017901

Classification

Generic

Dosage Form

CAPSULE

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA089007

FDA Approved

3/17/1986

TE Code

AA

On Market Since

4/16/2012

Pharmacological Classes

Barbiturate
Barbiturates
Central Nervous System Stimulant
Central Nervous System Stimulation
Methylxanthine
Xanthines

Price Statistics

The NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE has been published 633 times since Nov 28, 2013, and over the history we have for it it has risen 259.1%. The table below summarizes its recorded NADAC range and movement.

Current price$2.0089 per EA
All-time high$3.8847 (May 15, 2019)
All-time low$0.2999 (Mar 18, 2015)
52-week high$2.3000
52-week low$1.6931
Median price$2.2931
Average price$2.2989
Largest weekly change+397.0% (May 20, 2015)
Weeks tracked633
Tracking sinceNov 28, 2013

Price History

1W

+10.5%

1M

+10.5%

3M

+16.1%

6M

+3.3%

1Y

-9.6%

3Y

-24.6%

5Y

-39.6%

All

+259.1%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE, manufactured by Mayne Pharma, is $2.0089 per EA (NDC 51862017901), effective Aug 19, 2026.

How has the price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE has risen 259.1%. It has been tracked across 633 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE?

Since Nov 28, 2013, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE has ranged from a low of $0.2999 (Mar 18, 2015) to a high of $3.8847 (May 15, 2019), with a median of $2.2931 per EA.

Are there cheaper alternatives to BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE, is $1.6931 per EA — about 16% below BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE.

Who manufactures BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE?

BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG CAPSULE (NDC 51862017901) is labeled by Mayne Pharma, and CMS classifies it as a generic product.