Product Information
HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET is a generic product labeled by American Health Packaging, priced at $0.1361 per EA under NDC 60687039601. Its NADAC has been published 163 times since Aug 23, 2023.
FDA first approved this application on Oct 30, 2017. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 5 mg/1; mg/1
Manufacturer
American Health PackagingNDC
60687039601
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHEN; HYDROCODONE BITARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA210211FDA Approved
10/30/2017
TE Code
AA
On Market Since
6/27/2023
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has been published 163 times since Aug 23, 2023, and over the history we have for it it has risen 16.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1361 per EA |
|---|---|
| All-time high | $0.1518 (Jul 10, 2024) |
| All-time low | $0.1138 (Nov 22, 2023) |
| 52-week high | $0.1388 |
| 52-week low | $0.1273 |
| Median price | $0.1289 |
| Average price | $0.1305 |
| Largest weekly change | +28.8% (Dec 20, 2023) |
| Weeks tracked | 163 |
| Tracking since | Aug 23, 2023 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
American Health Packaging manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Hydrocodone Bitartrate and Acetaminophen market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Opioid Agonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET, manufactured by American Health Packaging, is $0.1361 per EA (NDC 60687039601), effective Sep 30, 2026.
How has the price of HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has risen 16.6%. It has been tracked across 163 weekly CMS publications since Aug 23, 2023.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?
Since Aug 23, 2023, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET has ranged from a low of $0.1138 (Nov 22, 2023) to a high of $0.1518 (Jul 10, 2024), with a median of $0.1289 per EA.
Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET, is $0.1066 per EA — about 22% below HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET.
Who manufactures HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET?
HYDROCODONE-ACETAMINOPHEN 5-325 MG TABLET (NDC 60687039601) is labeled by American Health Packaging, and CMS classifies it as a generic product.