Product Information
THEOPHYLLINE ER 450 MG TABLET is a generic product labeled by Alembic Pharmaceuticals Inc., priced at $1.0503 per EA under NDC 62332002631. Its NADAC has been published 90 times since Mar 30, 2016.
FDA first approved this application on Oct 27, 2010. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
450 mg/1
Manufacturer
Alembic Pharmaceuticals Inc.NDC
62332002631
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
THEOPHYLLINE ANHYDROUSApproval Type
Generic (ANDA)
FDA Application
ANDA090430FDA Approved
10/27/2010
TE Code
AB
On Market Since
1/29/2016
Pharmacological Classes
Price Statistics
The NADAC for THEOPHYLLINE ER 450 MG TABLET has been published 90 times since Mar 30, 2016, and over the history we have for it it has risen 72.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0503 per EA |
|---|---|
| All-time high | $1.9133 (Apr 16, 2025) |
| All-time low | $0.5902 (Nov 19, 2025) |
| 52-week high | $1.1638 |
| 52-week low | $0.5902 |
| Median price | $1.0180 |
| Average price | $1.0716 |
| Largest weekly change | +214.2% (Mar 19, 2025) |
| Weeks tracked | 90 |
| Tracking since | Mar 30, 2016 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of THEOPHYLLINE ER 450 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for THEOPHYLLINE ER 450 MG TABLET, manufactured by Alembic Pharmaceuticals Inc., is $1.0503 per EA (NDC 62332002631), effective Aug 19, 2026.
How has the price of THEOPHYLLINE ER 450 MG TABLET changed over time?
Over the history we have for it, the NADAC for THEOPHYLLINE ER 450 MG TABLET has risen 72.5%. It has been tracked across 90 weekly CMS publications since Mar 30, 2016.
What are the highest and lowest recorded NADAC prices for THEOPHYLLINE ER 450 MG TABLET?
Since Mar 30, 2016, the NADAC for THEOPHYLLINE ER 450 MG TABLET has ranged from a low of $0.5902 (Nov 19, 2025) to a high of $1.9133 (Apr 16, 2025), with a median of $1.0180 per EA.
Are there cheaper alternatives to THEOPHYLLINE ER 450 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as THEOPHYLLINE ER 450 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures THEOPHYLLINE ER 450 MG TABLET?
THEOPHYLLINE ER 450 MG TABLET (NDC 62332002631) is labeled by Alembic Pharmaceuticals Inc., and CMS classifies it as a generic product.