Product Information
THEOPHYLLINE ER 450 MG TABLET is a generic product labeled by Camber Pharmaceuticals Inc., priced at $1.0503 per EA under NDC 31722007801. Its NADAC has been published 75 times since Mar 19, 2025.
FDA first approved this application on Sep 8, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
450 mg/1
Manufacturer
Camber Pharmaceuticals Inc.NDC
31722007801
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
THEOPHYLLINE ANHYDROUSApproval Type
Generic (ANDA)
FDA Application
ANDA217422FDA Approved
9/8/2023
TE Code
AB
On Market Since
9/8/2023
Pharmacological Classes
Price Statistics
The NADAC for THEOPHYLLINE ER 450 MG TABLET has been published 75 times since Mar 19, 2025, and over the history we have for it it has declined 45.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0503 per EA |
|---|---|
| All-time high | $1.9133 (Apr 16, 2025) |
| All-time low | $0.5902 (Nov 19, 2025) |
| 52-week high | $1.1638 |
| 52-week low | $0.5902 |
| Median price | $1.0974 |
| Average price | $1.1641 |
| Largest weekly change | +45.0% (Dec 17, 2025) |
| Weeks tracked | 75 |
| Tracking since | Mar 19, 2025 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of THEOPHYLLINE ER 450 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for THEOPHYLLINE ER 450 MG TABLET, manufactured by Camber Pharmaceuticals Inc., is $1.0503 per EA (NDC 31722007801), effective Aug 19, 2026.
How has the price of THEOPHYLLINE ER 450 MG TABLET changed over time?
Over the history we have for it, the NADAC for THEOPHYLLINE ER 450 MG TABLET has declined 45.1%. It has been tracked across 75 weekly CMS publications since Mar 19, 2025.
What are the highest and lowest recorded NADAC prices for THEOPHYLLINE ER 450 MG TABLET?
Since Mar 19, 2025, the NADAC for THEOPHYLLINE ER 450 MG TABLET has ranged from a low of $0.5902 (Nov 19, 2025) to a high of $1.9133 (Apr 16, 2025), with a median of $1.0974 per EA.
Are there cheaper alternatives to THEOPHYLLINE ER 450 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as THEOPHYLLINE ER 450 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures THEOPHYLLINE ER 450 MG TABLET?
THEOPHYLLINE ER 450 MG TABLET (NDC 31722007801) is labeled by Camber Pharmaceuticals Inc., and CMS classifies it as a generic product.