Product Information

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM is a generic product labeled by Alembic Pharmaceuticals Inc., priced at $1.3353 per GM under NDC 62332058204. Its NADAC has been published 83 times since Dec 28, 2022.

FDA first approved this application on Apr 8, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM

Lidocaine and Prilocaine
$1.3353per GM

Strength

25; 25 mg/g; mg/g

NDC

62332058204

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

7/22/2026

Active Ingredients

LIDOCAINE; PRILOCAINE

Approval Type

Generic (ANDA)

FDA Application

ANDA213923

FDA Approved

4/8/2022

TE Code

AB

On Market Since

4/12/2022

Pharmacological Classes

Amide Local Anesthetic
Amide Local Anesthetic
Amides
Amides
Antiarrhythmic
Local Anesthesia
Local Anesthesia

Price Statistics

The NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has been published 83 times since Dec 28, 2022, and over the history we have for it it has risen 7.2%. The table below summarizes its recorded NADAC range and movement.

Current price$1.3353 per GM
All-time high$1.5054 (Dec 10, 2025)
All-time low$1.2462 (Dec 28, 2022)
52-week high$1.5054
52-week low$1.3340
Median price$1.3949
Average price$1.3915
Largest weekly change+13.8% (Mar 19, 2025)
Weeks tracked83
Tracking sinceDec 28, 2022

Price History

1W

0.0%

1M

0.0%

3M

+0.1%

6M

-4.9%

1Y

-7.9%

3Y

+7.2%

5Y

N/A

All

+7.2%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 83% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, manufactured by Alembic Pharmaceuticals Inc., is $1.3353 per GM (NDC 62332058204), effective Aug 19, 2026.

How has the price of LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM changed over time?

Over the history we have for it, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has risen 7.2%. It has been tracked across 83 weekly CMS publications since Dec 28, 2022.

What are the highest and lowest recorded NADAC prices for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

Since Dec 28, 2022, the NADAC for LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM has ranged from a low of $1.2462 (Dec 28, 2022) to a high of $1.5054 (Dec 10, 2025), with a median of $1.3949 per GM.

Are there cheaper alternatives to LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM, is $0.2211 per GM — about 83% below LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM.

Who manufactures LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM?

LIDOCAINE-PRILOCAINE 2.5%-2.5% CREAM (NDC 62332058204) is labeled by Alembic Pharmaceuticals Inc., and CMS classifies it as a generic product.