Product Information
ACYCLOVIR 5% OINTMENT is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.5362 per GM under NDC 65162083594. Its NADAC has been published 595 times since Apr 1, 2015.
FDA first approved this application on Jun 18, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Acyclovir market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/g
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162083594
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ACYCLOVIRApproval Type
Generic (ANDA)
FDA Application
ANDA204605FDA Approved
6/18/2014
TE Code
AB
On Market Since
1/3/2014
Pharmacological Classes
Price Statistics
The NADAC for ACYCLOVIR 5% OINTMENT has been published 595 times since Apr 1, 2015, and over the history we have for it it has declined 97.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5362 per GM |
|---|---|
| All-time high | $19.4391 (May 13, 2015) |
| All-time low | $0.4269 (Nov 20, 2024) |
| 52-week high | $0.6429 |
| 52-week low | $0.5153 |
| Median price | $1.3693 |
| Average price | $5.1919 |
| Largest weekly change | +46.7% (Aug 17, 2022) |
| Weeks tracked | 595 |
| Tracking since | Apr 1, 2015 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 36% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ACYCLOVIR 5% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 5% OINTMENT, manufactured by Amneal Pharmaceuticals LLC, is $0.5362 per GM (NDC 65162083594), effective Aug 19, 2026.
How has the price of ACYCLOVIR 5% OINTMENT changed over time?
Over the history we have for it, the NADAC for ACYCLOVIR 5% OINTMENT has declined 97.2%. It has been tracked across 595 weekly CMS publications since Apr 1, 2015.
What are the highest and lowest recorded NADAC prices for ACYCLOVIR 5% OINTMENT?
Since Apr 1, 2015, the NADAC for ACYCLOVIR 5% OINTMENT has ranged from a low of $0.4269 (Nov 20, 2024) to a high of $19.4391 (May 13, 2015), with a median of $1.3693 per GM.
Are there cheaper alternatives to ACYCLOVIR 5% OINTMENT?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ACYCLOVIR 5% OINTMENT, is $0.3421 per GM — about 36% below ACYCLOVIR 5% OINTMENT.
Who manufactures ACYCLOVIR 5% OINTMENT?
ACYCLOVIR 5% OINTMENT (NDC 65162083594) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.