Product Information
DOTTI 0.05 MG PATCH is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $7.7678 per EA under NDC 65162099308. Its NADAC has been published 364 times since Jul 10, 2019.
Strength
.05 mg/d
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162099308
Classification
Generic
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA211293On Market Since
2/4/2019
Pharmacological Classes
Price Statistics
The NADAC for DOTTI 0.05 MG PATCH has been published 364 times since Jul 10, 2019, and over the history we have for it it has declined 5.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.7678 per EA |
|---|---|
| All-time high | $9.2907 (Feb 16, 2022) |
| All-time low | $4.9914 (Nov 20, 2024) |
| 52-week high | $7.7678 |
| 52-week low | $6.8561 |
| Median price | $7.2018 |
| Average price | $7.2206 |
| Largest weekly change | +28.3% (Aug 21, 2024) |
| Weeks tracked | 364 |
| Tracking since | Jul 10, 2019 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of DOTTI 0.05 MG PATCH?
The current National Average Drug Acquisition Cost (NADAC) for DOTTI 0.05 MG PATCH, manufactured by Amneal Pharmaceuticals LLC, is $7.7678 per EA (NDC 65162099308), effective Jun 24, 2026.
How has the price of DOTTI 0.05 MG PATCH changed over time?
Over the history we have for it, the NADAC for DOTTI 0.05 MG PATCH has declined 5.0%. It has been tracked across 364 weekly CMS publications since Jul 10, 2019.
What are the highest and lowest recorded NADAC prices for DOTTI 0.05 MG PATCH?
Since Jul 10, 2019, the NADAC for DOTTI 0.05 MG PATCH has ranged from a low of $4.9914 (Nov 20, 2024) to a high of $9.2907 (Feb 16, 2022), with a median of $7.2018 per EA.
Are there cheaper alternatives to DOTTI 0.05 MG PATCH?
4 NADAC-published products share the same active ingredient, strength, and dosage form as DOTTI 0.05 MG PATCH, but none are currently priced below it.
Who manufactures DOTTI 0.05 MG PATCH?
DOTTI 0.05 MG PATCH (NDC 65162099308) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.
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