Product Information

DIVIGEL 0.5 MG GEL PACKET is a brand product labeled by Vertical Pharmaceuticals, LLC, priced at $5.3966 per EA under NDC 68025006630. Its NADAC has been published 589 times since Mar 18, 2015.

DIVIGEL 0.5 MG GEL PACKET

estradiol
$5.3966per EA

Strength

.5 mg/.5g

NDC

68025006630

Classification

Brand

Dosage Form

GEL

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

ESTRADIOL

Approval Type

New Drug (NDA)

FDA Application

NDA022038

On Market Since

10/27/2014

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for DIVIGEL 0.5 MG GEL PACKET has been published 589 times since Mar 18, 2015, and over the history we have for it it has risen 94.0%. The table below summarizes its recorded NADAC range and movement.

Current price$5.3966 per EA
All-time high$5.4255 (Apr 10, 2024)
All-time low$2.7811 (Mar 18, 2015)
52-week high$5.3991
52-week low$5.3832
Median price$4.5748
Average price$4.5386
Largest weekly change+15.9% (Apr 22, 2015)
Weeks tracked589
Tracking sinceMar 18, 2015

Price History

1W

0.0%

1M

-0.0%

3M

+0.0%

6M

+0.0%

1Y

+0.1%

3Y

-0.5%

5Y

+12.4%

All

+94.0%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 75% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIVIGEL 0.5 MG GEL PACKET?

The current National Average Drug Acquisition Cost (NADAC) for DIVIGEL 0.5 MG GEL PACKET, manufactured by Vertical Pharmaceuticals, LLC, is $5.3966 per EA (NDC 68025006630), effective Jun 24, 2026.

How has the price of DIVIGEL 0.5 MG GEL PACKET changed over time?

Over the history we have for it, the NADAC for DIVIGEL 0.5 MG GEL PACKET has risen 94.0%. It has been tracked across 589 weekly CMS publications since Mar 18, 2015.

What are the highest and lowest recorded NADAC prices for DIVIGEL 0.5 MG GEL PACKET?

Since Mar 18, 2015, the NADAC for DIVIGEL 0.5 MG GEL PACKET has ranged from a low of $2.7811 (Mar 18, 2015) to a high of $5.4255 (Apr 10, 2024), with a median of $4.5748 per EA.

Are there cheaper alternatives to DIVIGEL 0.5 MG GEL PACKET?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, ESTRADIOL 0.1% (0.5 MG) GEL PKT, is $1.3243 per EA — about 75% below DIVIGEL 0.5 MG GEL PACKET.

Who manufactures DIVIGEL 0.5 MG GEL PACKET?

DIVIGEL 0.5 MG GEL PACKET (NDC 68025006630) is labeled by Vertical Pharmaceuticals, LLC, and CMS classifies it as a brand product.