Product Information
ESTRADIOL 0.1% (0.5 MG) GEL PKT is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $1.3243 per EA under NDC 45802020230. Its NADAC has been published 125 times since Feb 7, 2024.
Strength
.5 mg/.5g
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802020230
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA216524On Market Since
12/7/2023
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has been published 125 times since Feb 7, 2024, and over the history we have for it it has declined 60.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3243 per EA |
|---|---|
| All-time high | $3.4167 (Apr 10, 2024) |
| All-time low | $1.1300 (Nov 20, 2024) |
| 52-week high | $2.1810 |
| 52-week low | $1.3243 |
| Median price | $1.8933 |
| Average price | $1.9654 |
| Largest weekly change | -47.1% (Apr 17, 2024) |
| Weeks tracked | 125 |
| Tracking since | Feb 7, 2024 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.1% (0.5 MG) GEL PKT?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (0.5 MG) GEL PKT, manufactured by Padagis Israel Pharmaceuticals Ltd, is $1.3243 per EA (NDC 45802020230), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.1% (0.5 MG) GEL PKT changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has declined 60.4%. It has been tracked across 125 weekly CMS publications since Feb 7, 2024.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (0.5 MG) GEL PKT?
Since Feb 7, 2024, the NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has ranged from a low of $1.1300 (Nov 20, 2024) to a high of $3.4167 (Apr 10, 2024), with a median of $1.8933 per EA.
Are there cheaper alternatives to ESTRADIOL 0.1% (0.5 MG) GEL PKT?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as ESTRADIOL 0.1% (0.5 MG) GEL PKT, but none are currently priced below it.
Who manufactures ESTRADIOL 0.1% (0.5 MG) GEL PKT?
ESTRADIOL 0.1% (0.5 MG) GEL PKT (NDC 45802020230) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.
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