Product Information
DIVIGEL 1 MG GEL PACKET is a brand product labeled by Vertical Pharmaceuticals, LLC, priced at $5.3728 per GM under NDC 68025006730. Its NADAC has been published 606 times since Jan 14, 2015.
FDA first approved this application on Jun 4, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1 mg/g
Manufacturer
Vertical Pharmaceuticals, LLCNDC
68025006730
Classification
Brand
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022038FDA Approved
6/4/2007
TE Code
AB
On Market Since
10/27/2014
Pharmacological Classes
Price Statistics
The NADAC for DIVIGEL 1 MG GEL PACKET has been published 606 times since Jan 14, 2015, and over the history we have for it it has risen 87.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $5.3728 per GM |
|---|---|
| All-time high | $5.4003 (Jun 14, 2023) |
| All-time low | $2.8663 (Jan 14, 2015) |
| 52-week high | $5.3889 |
| 52-week low | $5.3692 |
| Median price | $4.5829 |
| Average price | $4.5244 |
| Largest weekly change | +11.4% (Mar 18, 2015) |
| Weeks tracked | 606 |
| Tracking since | Jan 14, 2015 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 79% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIVIGEL 1 MG GEL PACKET?
The current National Average Drug Acquisition Cost (NADAC) for DIVIGEL 1 MG GEL PACKET, manufactured by Vertical Pharmaceuticals, LLC, is $5.3728 per GM (NDC 68025006730), effective Aug 19, 2026.
How has the price of DIVIGEL 1 MG GEL PACKET changed over time?
Over the history we have for it, the NADAC for DIVIGEL 1 MG GEL PACKET has risen 87.4%. It has been tracked across 606 weekly CMS publications since Jan 14, 2015.
What are the highest and lowest recorded NADAC prices for DIVIGEL 1 MG GEL PACKET?
Since Jan 14, 2015, the NADAC for DIVIGEL 1 MG GEL PACKET has ranged from a low of $2.8663 (Jan 14, 2015) to a high of $5.4003 (Jun 14, 2023), with a median of $4.5829 per GM.
Are there cheaper alternatives to DIVIGEL 1 MG GEL PACKET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ESTRADIOL 0.1% (1 MG) GEL PKT, is $1.1272 per GM — about 79% below DIVIGEL 1 MG GEL PACKET.
Who manufactures DIVIGEL 1 MG GEL PACKET?
DIVIGEL 1 MG GEL PACKET (NDC 68025006730) is labeled by Vertical Pharmaceuticals, LLC, and CMS classifies it as a brand product.