Product Information

DIVIGEL 1.25 MG GEL PACKET is a brand product labeled by Vertical Pharmaceuticals, LLC, priced at $4.2906 per GM under NDC 68025008630. Its NADAC has been published 184 times since Jun 22, 2022.

DIVIGEL 1.25 MG GEL PACKET

estradiol
$4.2906per GM

Strength

1.25 mg/1.25g

NDC

68025008630

Classification

Brand

Dosage Form

GEL

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

ESTRADIOL

Approval Type

New Drug (NDA)

FDA Application

NDA022038

On Market Since

12/17/2019

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for DIVIGEL 1.25 MG GEL PACKET has been published 184 times since Jun 22, 2022, and over the history we have for it it has risen 3.6%. The table below summarizes its recorded NADAC range and movement.

Current price$4.2906 per GM
All-time high$4.3230 (Feb 12, 2025)
All-time low$4.1422 (Jun 22, 2022)
52-week high$4.3227
52-week low$4.2790
Median price$4.3102
Average price$4.2945
Largest weekly change+4.1% (Sep 14, 2022)
Weeks tracked184
Tracking sinceJun 22, 2022

Price History

1W

0.0%

1M

+0.2%

3M

+0.3%

6M

-0.4%

1Y

-0.7%

3Y

-0.5%

5Y

N/A

All

+3.6%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 73% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIVIGEL 1.25 MG GEL PACKET?

The current National Average Drug Acquisition Cost (NADAC) for DIVIGEL 1.25 MG GEL PACKET, manufactured by Vertical Pharmaceuticals, LLC, is $4.2906 per GM (NDC 68025008630), effective Jun 24, 2026.

How has the price of DIVIGEL 1.25 MG GEL PACKET changed over time?

Over the history we have for it, the NADAC for DIVIGEL 1.25 MG GEL PACKET has risen 3.6%. It has been tracked across 184 weekly CMS publications since Jun 22, 2022.

What are the highest and lowest recorded NADAC prices for DIVIGEL 1.25 MG GEL PACKET?

Since Jun 22, 2022, the NADAC for DIVIGEL 1.25 MG GEL PACKET has ranged from a low of $4.1422 (Jun 22, 2022) to a high of $4.3230 (Feb 12, 2025), with a median of $4.3102 per GM.

Are there cheaper alternatives to DIVIGEL 1.25 MG GEL PACKET?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, ESTRADIOL 0.1% (1.25 MG) GEL PK, is $1.1440 per GM — about 73% below DIVIGEL 1.25 MG GEL PACKET.

Who manufactures DIVIGEL 1.25 MG GEL PACKET?

DIVIGEL 1.25 MG GEL PACKET (NDC 68025008630) is labeled by Vertical Pharmaceuticals, LLC, and CMS classifies it as a brand product.