Product Information
TOPIRAMATE ER 25 MG CAPSULE is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $4.2076 per EA under NDC 68382086306. Its NADAC has been published 157 times since Aug 23, 2023.
FDA first approved this application on Nov 24, 2017. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382086306
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA207382FDA Approved
11/24/2017
TE Code
AB1
On Market Since
9/10/2024
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE ER 25 MG CAPSULE has been published 157 times since Aug 23, 2023, and over the history we have for it it has declined 54.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $4.2076 per EA |
|---|---|
| All-time high | $9.3295 (Oct 11, 2023) |
| All-time low | $2.8599 (Nov 20, 2024) |
| 52-week high | $4.4743 |
| 52-week low | $3.7241 |
| Median price | $4.9147 |
| Average price | $5.3246 |
| Largest weekly change | -46.2% (Nov 20, 2024) |
| Weeks tracked | 157 |
| Tracking since | Aug 23, 2023 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 94% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TOPIRAMATE ER 25 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE ER 25 MG CAPSULE, manufactured by Zydus Pharmaceuticals (USA) Inc., is $4.2076 per EA (NDC 68382086306), effective Aug 19, 2026.
How has the price of TOPIRAMATE ER 25 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE ER 25 MG CAPSULE has declined 54.9%. It has been tracked across 157 weekly CMS publications since Aug 23, 2023.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE ER 25 MG CAPSULE?
Since Aug 23, 2023, the NADAC for TOPIRAMATE ER 25 MG CAPSULE has ranged from a low of $2.8599 (Nov 20, 2024) to a high of $9.3295 (Oct 11, 2023), with a median of $4.9147 per EA.
Are there cheaper alternatives to TOPIRAMATE ER 25 MG CAPSULE?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TOPIRAMATE 25 MG SPRINKLE CAP, is $0.2547 per EA — about 94% below TOPIRAMATE ER 25 MG CAPSULE.
Who manufactures TOPIRAMATE ER 25 MG CAPSULE?
TOPIRAMATE ER 25 MG CAPSULE (NDC 68382086306) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.