Product Information
LOTEPREDNOL ETABONATE 0.5% DRP is a generic product labeled by Oceanside Pharmaceuticals, priced at $20.2655 per ML under NDC 68682029910. Its NADAC has been published 259 times since Oct 21, 2020.
FDA first approved this application on Mar 9, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/mL
Manufacturer
Oceanside PharmaceuticalsNDC
68682029910
Classification
Generic
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Effective Date
9/17/2025
Active Ingredients
LOTEPREDNOL ETABONATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020583FDA Approved
3/9/1998
TE Code
AB
On Market Since
7/1/2019
Pharmacological Classes
Price Statistics
The NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has been published 259 times since Oct 21, 2020, and over the history we have for it it has declined 49.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $20.2655 per ML |
|---|---|
| All-time high | $40.4678 (Nov 11, 2020) |
| All-time low | $8.9795 (Apr 23, 2025) |
| Median price | $30.1471 |
| Average price | $28.3660 |
| Largest weekly change | -33.1% (Dec 20, 2023) |
| Weeks tracked | 259 |
| Tracking since | Oct 21, 2020 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
-21.2%
5Y
-41.8%
All
-49.9%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 48% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Oceanside Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
loteprednol etabonate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Corticosteroid class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOTEPREDNOL ETABONATE 0.5% DRP?
The current National Average Drug Acquisition Cost (NADAC) for LOTEPREDNOL ETABONATE 0.5% DRP, manufactured by Oceanside Pharmaceuticals, is $20.2655 per ML (NDC 68682029910), effective Oct 1, 2025.
How has the price of LOTEPREDNOL ETABONATE 0.5% DRP changed over time?
Over the history we have for it, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has declined 49.9%. It has been tracked across 259 weekly CMS publications since Oct 21, 2020.
What are the highest and lowest recorded NADAC prices for LOTEPREDNOL ETABONATE 0.5% DRP?
Since Oct 21, 2020, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has ranged from a low of $8.9795 (Apr 23, 2025) to a high of $40.4678 (Nov 11, 2020), with a median of $30.1471 per ML.
Are there cheaper alternatives to LOTEPREDNOL ETABONATE 0.5% DRP?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOTEPREDNOL ETABONATE 0.5% DRP, is $10.4737 per ML — about 48% below LOTEPREDNOL ETABONATE 0.5% DRP.
Who manufactures LOTEPREDNOL ETABONATE 0.5% DRP?
LOTEPREDNOL ETABONATE 0.5% DRP (NDC 68682029910) is labeled by Oceanside Pharmaceuticals, and CMS classifies it as a generic product.